CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID446
Family Name Cyclin-dependent kinase 8 Inhibitor Oxindole 94 Family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00191658 Functional Category Investigative Drug
Superfamily CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Amrinone Superfamily
Class Class 11

Cousin Family NamesSeedsMembers
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Amrino... 3 55
Cytochrome P450 11B1, mitochondrial Inhibitor Metyrapone Family 9 243
Prothrombin Inhibitor Ximelegatran Family 8 157
ABC294640 family 5 75
cGMP-dependent 3',5'-cyclic phosphodiesterase Inhibitor CP-461... 4 34
Platelet-derived growth factor receptor alpha and Platelet-der... 2 1
Transient receptor potential cation channel subfamily V member... 6 23
D(4) dopamine receptor Ligand ABT-670 Family 4 14
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
Neuropeptide Y receptor type 5 ligand (5E)-5-[(4S,5S)-4-(4-flu... 18 3
Cell division cycle 7-related protein kinase and Protein DBF4 ... 1 5
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 1
Nociceptin receptor and Mu-type opioid receptor ligand N-[(1R,... 4 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00191658 DNC001076 Investigative Drug Oxindole 94
CFAMM00191654 DNC008690 Investigative Drug NSC-683634

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27293 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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