CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Peptide deformylase, mitochondrial Inhibitor Tylophorinidine Family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00192091 Functional Category Investigative Drug
Superfamily Glaziovine Superfamily
Class Class 66

Cousin Family NamesSeedsMembers
Delta-type opioid receptor ligand opiate analog Codeine Family 15 184
u-type opioid receptor ligand opiate analog Buprenorphine Family 78 234
Nicotinic acetylcholine receptor alpha subunit Ligand benzylis... 4 18
D(1B) dopamine receptor Ligand Apomorphine Family 30 271
Neuronal acetylcholine receptor subunit alpha-2 Ligand Metocur... 18 169
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Glaziovine family 1 4
D(3) dopamine receptor Ligand U-99194A Family 7 33
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Tumor necrosis factor Inhibitor Y-39041 Family 9 51
D(2) dopamine receptor and D(1A) dopamine receptor Ligand 3-br... 2 1
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 41
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
5-hydroxytryptamine receptor 2A and D(1A) dopamine receptor Li... 8 33
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Tubulin beta chain Inhibitor Colchinol Family 3 109
D(2) dopamine receptor and Sodium-dependent dopamine transport... 6 10
D(2) dopamine receptor and D(1A) dopamine receptor Ligand 3-ch... 2 0
D(2) dopamine receptor Ligand (s)-secoantioquine Family 1 10
Sodium-dependent dopamine transporter Inhibitor Secocularidine... 3 9
Kappa-type opioid receptor Ligand Morphinan Cyclic Imine Analo... 20 0
5-hydroxytryptamine receptor 1A ligand SureCN7035190 family 10 17
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 7 0
D(1A) dopamine receptor ligand DOXANTHINE family 3 0
D(1A) dopamine receptor and D(3) dopamine receptor ligand N,N-... 3 1
Transient receptor potential cation channel subfamily V member... 14 7
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 11 2
Sigma non-opioid intracellular receptor 1 ligand BAS 04057753 ... 5 8
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 28
7-dehydrocholesterol reductase inhibitor 2-[2-(4-chlorophenyl)... 2 3
Histamine H3 receptor and Sodium-dependent serotonin transport... 6 1
Putative Bioactive 5-hexyl-2-[4-[(4-methylpiperazin-1-yl)methy... 2 0
Alpha-2A adrenergic receptor and Alpha-2C adrenergic receptor ... 2 26


External ID

Functional Category

Molecule Name

CFAMM00192102 DNC013768 Investigative Drug N-isopropylnorlitebamineN-methoiodide
CFAMM00192099 DNC001113 Investigative Drug Pergularinine
CFAMM00192098 DNC008007 Investigative Drug [(R)-(+)-deoxytylophorinidine
CFAMM00192094 DNC008008 Investigative Drug DCB-3503
CFAMM00192091 DNC001477 Investigative Drug Tylophorinidine
CFAMM00192105 DNC013770 Investigative Drug N-benzylnorlitebamine
CFAMM00192104 DNC013772 Investigative Drug N-isobutylnorlitebamine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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