CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID467
Family Name Inhibitor of nuclear factor kappa-B kinase subunit epsilon and Nuclear factor NF-kappa-B p100 subunit Inhibitor PS-1145 Family
No. of Seeds 1 No. of Other Members 4
Family Centroid CFAMM00211909 Functional Category Investigative Drug
Superfamily Inhibitor of nuclear factor kappa-B kinase subunit epsilon Inhibitor MLN0415 Superfamily
Class Class 1033

Cousin Family NamesSeedsMembers
Glycogen phosphorylase, muscle form Inhibitor PSN357 Family 3 253
D(4) dopamine receptor Ligand SPI-376 Family 7 84
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(4-chlorophenyl)-5-... 2 8
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(4... 4 21
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 93
Acetylcholinesterase and Cholinesterase Inhibitor Lipocrine Fa... 18 36
Cannabinoid receptor 1 Ligand N-phenyl-5,6-dip-tolylpyrazine-2... 11 26
14-alpha sterol demethylase Inhibitor CP-320626 Family 13 76
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 3-chlo... 3 2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 5 22
Ceramide glucosyltransferase inhibitor AGN-PC-07YS0C family 4 3
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor 2-... 18 2
Substance-P receptor and Neuromedin-K receptor ligand SureCN88... 4 14
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-009GH... 8 10
Dual specificity protein kinase CLK4 and Mitogen-activated pro... 1 1
Coagulation factor X inhibitor 3-chloro-N-[(1S,2S)-2-[[4-(2-ox... 22 3
Gonadotropin-releasing hormone receptor ligand 1-adamantyl-[2-... 3 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00211909 DNC001156 Investigative Drug PS-1145

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27701 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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