CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-4-isobutyl-benzamide Family
No. of Seeds 4 No. of Other Members 43
Family Centroid CFAMM00176136 Functional Category Investigative Drug
Superfamily Histone deacetylase 1 and Arachidonate 5-lipoxygenase Binder Superfamily
Class Class 1125

Cousin Family NamesSeedsMembers
DNA Binder Procarbazine Family 8 358
C-X-C chemokine receptor type 1 and C-X-C chemokine receptor t... 5 30
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-m... 8 37
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-bi... 5 14
Histone deacetylase 1 Inhibitor 8-(3-benzoyl-ureido)-octanoic ... 7 13
Glutamate carboxypeptidase 2 Inhibitor 2-(3-carbamoylbenzyl)-5... 2 1
Histone deacetylase 1 Inhibitor N-hydroxy-6-oxo-6-phenylhexana... 7 7
Histone deacetylase 1 Inhibitor N-hydroxy-7-(naphthalen-2-yl)-... 3 2
Histone deacetylase 1 Inhibitor 8-(4-bromophenyl)-n-hydroxy-8-... 2 1
Histone deacetylase 1 Inhibitor N-hydroxy-8-(naphthalen-2-yl)n... 6 3
Aminopeptidase N Inhibitor N1,2-dibenzyl-n3-hydroxymalonamide ... 5 23
Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-n-methyl-2-nap... 3 3
Arachidonate 5-lipoxygenase Inhibitor Phenanthrene-3-carboxyli... 7 4
Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-n-methyl-benza... 3 9
Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-n-methyl-2,3,3... 1 0
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 2 80
Lethal factor inhibitor Flurofamide family 1 0
Protease inhibitor SureCN6172401 family 1 1


External ID

Functional Category

Molecule Name

CFAMM00176173 DNC008010 Investigative Drug 4-tert-butyl-N-hydroxybenzamide
CFAMM00176136 DNC011615 Investigative Drug N-Hydroxy-4-isobutyl-benzamide
CFAMM00176186 DPR000147 Investigative Drug M-carboxycinnamic acid bishydroxamide
CFAMM00176184 DNC011655 Investigative Drug N-Hydroxy-4-iodo-benzamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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