CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID516
Family Name Histamine N-methyltransferase Inhibitor S-adenosyl-l-homocysteine Family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00212896 Functional Category Investigative Drug
Superfamily Adenosylhomocysteinase and Thyroid hormone receptor Binder Superfamily
Class Class 1506

Cousin Family NamesSeedsMembers
Adenosine receptor A3 ligand purine nucleoside Adenosine Family 47 847
DNA Binder purine nucleoside Adenosine analog Nelarabine Family 2 10
Bucladesine family 1 1
Adenosine receptor A2a Ligand Atl-146e Family 33 94
P2Y purinoceptor 12 Inhibitor Ar-c69931 Mx Family 10 18
TG-C family 11 208
Reverse transcriptase Inhibitor Amdoxovir Family 1 2
Adenosylhomocysteinase Inhibitor D-eritadenine Family 2 1
Adenosine deaminase Inhibitor (2s,3r)-3-(6-amino-9h-purin-9-yl... 4 30
Adenosylhomocysteinase Inhibitor 4(z)-(5'-deoxyadenosin-5'-yli... 2 1
cAMP-dependent protein kinase type I-alpha regulatory subunit ... 12 0
Asparagine synthetase [glutamine-hydrolyzing] inhibitor (2R)-2... 2 1
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 16 6
Adenosine receptor A1 ligand CHEMBL258759 family 2 3
Adenosine receptor A1 and Adenosine receptor A2b ligand (2R,3R... 9 0
Adenosine receptor A2a and Adenosine receptor A2b ligand Cgs-2... 1 2
Putative Bioactive [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-di... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00212891 DNC001332 Investigative Drug Sinefungin
CFAMM00212896 DNC003025 Investigative Drug S-Adenosyl-L-Homocysteine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27254 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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