CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID519
Family Name 5-hydroxytryptamine receptor Ligand Sl65.0472 Family
No. of Seeds 2 No. of Other Members 16
Family Centroid CFAMM00212918 Functional Category Investigative Drug
Superfamily 5-hydroxytryptamine receptor and Muscarinic acetylcholine receptor M1 Binder Superfamily
Class Class 1642

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase C Inhibitor SNS-314 Family 2 75
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Aurora kinase A Inhibitor ABT-348 Family 20 49
Beta-secretase 1 Inhibitor 6-[2-(1h-indol-6-yl)ethyl]pyridin-2... 10 43
TGF-beta receptor type-1 Ligand 4-pyridin-2-yl-5-quinolin-4-yl... 4 23
Mitogen-activated protein kinase 14 Inhibitor 4-(2-ethyl-4-m-t... 14 41
Vascular endothelial growth factor receptor 2 Ligand 3-(4-amin... 2 5
Cyclin-dependent kinase 5 Inhibitor 1-phenyl-3-(2-(pyridin-4-y... 3 53
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-264... 6 32
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 22
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(4-acet... 4 12
Mitogen-activated protein kinase 14 inhibitor 4-[4-(4-fluoroph... 2 0
Neuropeptide Y receptor type 5 ligand N-[[(1S,5R)-3-(1-phenyle... 5 1
Vascular endothelial growth factor receptor 2 and Mast/stem ce... 10 27
Serine/threonine-protein kinase Chk1 inhibitor SureCN3070314 f... 16 32
DNA-(apurinic or apyrimidinic site) lyase and Neuropeptide S r... 1 4
Amine oxidase [flavin-containing] B inhibitor 4-(4-fluoropheny... 3 4
Platelet-activating factor receptor ligand Foropafant family 2 0
Mitogen-activated protein kinase 14 inhibitor N-[4-[2-ETHYL-4-... 4 5
Vascular endothelial growth factor receptor 2 and Platelet-der... 3 3
Vascular endothelial growth factor receptor 1 and Receptor-typ... 1 0
Serine/threonine-protein kinase Chk1 inhibitor 5-[5-(1-methylp... 3 2
Cell division cycle 7-related protein kinase and Protein DBF4 ... 2 1
Vascular endothelial growth factor receptor 2 and Vascular end... 4 1
Eukaryotic translation initiation factor 2-alpha kinase 3 and ... 5 0
Eukaryotic translation initiation factor 2-alpha kinase 3 inhi... 2 1
Eukaryotic translation initiation factor 2-alpha kinase 3 inhi... 1 0
Vascular endothelial growth factor receptor 2 ligand N-(1,3-Th... 4 4
Protein-cysteine N-palmitoyltransferase porcupine inhibitor 2-... 5 2
Transient receptor potential cation channel subfamily V member... 1 0
Mitogen-activated protein kinase 14 inhibitor 303163-37-3 family 1 2
Vascular endothelial growth factor receptor 2 ligand Thienopyr... 2 2
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 2 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00212918 DNC001342 Investigative Drug SL65.0472

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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