CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID535
Family Name Fibroblast growth factor receptor Ligand SU5403 Family
No. of Seeds 8 No. of Other Members 8
Family Centroid CFAMM00213045 Functional Category Investigative Drug
Superfamily Fibroblast growth factor receptor Ligand SU5403 Superfamily
Class Class 62

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand catecholamine group Isoprotere... 7 130
Histamine H1 receptor Ligand Terfenadine Family 3 50
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Alpha adrenergic receptor Ligand Pseudoephedrine Family 4 96
Opioid receptor ligand opiate Levorphanol Family 18 537
Alpha adrenergic receptor ligand catecholamine Phenylephrine F... 4 39
Beta-2 adrenergic receptor ligand catecholamine Orciprenaline ... 13 13
Beta-2 adrenergic receptor ligand catecholamine Salbutamol Family 10 90
Beta-2 adrenergic receptor Ligand Bambuterol Family 4 9
Beta-1 adrenergic receptor Ligand Metoprolol Family 29 90
Muscarinic acetylcholine receptor M3 Ligand Tolterodine Family 8 171
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Muscarinic acetylcholine receptor M1 Ligand Trihexyphenidyl Fa... 14 199
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Kappa-type opioid receptor Ligand Dezocine Family 36 46
Mu-type opioid receptor ligand opiate Methadyl Acetate Family 5 9
Mu-type opioid receptor Ligand Alvimopan Family 32 325
Oestrogen receptor Ligand Lasofoxifene Family 19 152
Nicotinic acetylcholine receptor Ligand Benztropine Mesylate F... 10 20
Noradrenergic re-uptake Inhibitor Desvenalfaxine Succinate Family 2 4
Eptazocine Hbr family 6 8
Noradrenergic re-uptake and Opioid receptor Ligand Tapentadol ... 21 79
Acolbifene family 10 115
5-hydroxytryptamine receptor 1A Ligand (s)-uh-301 Family 35 20
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Sulfen... 5 13
Histamine H3 receptor Ligand UCL-2138 Family 23 172
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 25 50
Acetylcholinesterase and Cholinesterase Inhibitor N,n'-(1',10'... 12 8
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Cytochrome P450 2D6 Inhibitor Bs 7840 Family 4 9
Sodium-dependent dopamine transporter and Sodium-dependent nor... 9 16
Potassium voltage-gated channel subfamily A member 5 Ligand 2-... 3 1
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 7 19
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 41
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 11 3
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 11
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Potassium voltage-gated channel subfamily H member 2 Ligand [1... 2 23
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 9 7
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 44 3
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-ri... 5 12
Sodium-dependent dopamine transporter and Sodium-dependent nor... 5 2
Sodium-dependent dopamine transporter and Sodium-dependent nor... 4 19
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 12
Glutamate receptor ionotropic, NMDA 3A and Glutamate receptor ... 2 1
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 1 2
Vesicular acetylcholine transporter inhibitor BENZOVESAMICOL f... 7 4
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 8
Sodium-dependent dopamine transporter and Sodium-dependent ser... 6 0
Estrogen receptor and Estrogen receptor beta ligand (2R,3R,4S)... 3 0
Histamine H3 receptor ligand cyclohexyl-[4-(3-piperidin-1-ylpr... 4 1
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 1 0
Transporter and Sodium-dependent serotonin transporter inhibit... 1 5
Kappa-type opioid receptor ligand CHEMBL2367762 family 2 0
Sigma non-opioid intracellular receptor 1 ligand (1S,4R,5R)-7-... 2 7
Histamine H3 receptor and Sodium-dependent serotonin transport... 3 6
Vesicular acetylcholine transporter inhibitor (1R,2R)-2-spiro[... 3 2
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 6
Vesicular acetylcholine transporter inhibitor (2R,3R)-5-(3-flu... 2 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 1
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 2
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 1 0
Phenylalanine--tRNA ligase alpha subunit inhibitor TCMDC-14030... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00213043 CHEMBL107104 Bioactive SureCN7334903
CFAMM00213050 CHEMBL108120 Bioactive SureCN8972350
CFAMM00213048 CHEMBL68881 Bioactive AGN-PC-00PJP6
CFAMM00213046 CHEMBL69967 Bioactive 1-[(2S)-2-hydroxy-3-(4-hydroxyphenyl)propyl]-4-[(4-methylphenyl)methyl]piperidin-4-ol
CFAMM00213045 DNC001387 Investigative Drug SU5403

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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