CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name C-C chemokine receptor type 5 Ligand Sch 351125 Family
No. of Seeds 6 No. of Other Members 29
Family Centroid CFAMM00176268 Functional Category Investigative Drug
Superfamily C-C chemokine receptor type 5 Binder Superfamily
Class Class 1374

Cousin Family NamesSeedsMembers
Histamine H1 receptor ligand tricyclic antidepressant Loratadi... 5 163
Substance-P receptor Ligand TAK-637 Family 18 63
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
C-C chemokine receptor type 5 Ligand GT-1282 Family 21 14
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
Neuronal acetylcholine receptor subunit alpha-7 and Acetylchol... 2 3
C-C chemokine receptor type 5 ligand AC1NUXE1 family 12 7
C-C chemokine receptor type 5 ligand 6-chloro-N-[(3R)-3-[4-[(5... 16 4
Macrophage colony-stimulating factor 1 receptor ligand SureCN1... 2 2


External ID

Functional Category

Molecule Name

CFAMM00176285 CHEMBL139559 Bioactive AC1NUINZ
CFAMM00176297 CHEMBL323172 Bioactive [4-[4-[(Z)-C-(4-bromophenyl)-N-methoxycarbonimidoyl]piperidin-1-yl]-4-methylpiperidin-1-yl]-(2,4-dimethylpyridin-3-yl)methanone
CFAMM00176296 CHEMBL138285 Bioactive AC1NULRB
CFAMM00176294 CHEMBL105821 Bioactive [4-[4-[(Z)-C-(4-bromophenyl)-N-ethoxycarbonimidoyl]piperidin-1-yl]-4-methylpiperidin-1-yl]-(2,4-dimethylpyridin-3-yl)methanone
CFAMM00176265 DNC001107 Investigative Drug PDGF gene therapy
CFAMM00176268 DNC001303 Investigative Drug SCH 351125

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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