CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Histamine H3 receptor and Histamine H4 receptor Ligand Thioperamide Family
No. of Seeds 8 No. of Other Members 12
Family Centroid CFAMM00213366 Functional Category Investigative Drug
Superfamily Histamine H3 receptor Ligand Cipralisant Superfamily
Class Class 464

Cousin Family NamesSeedsMembers
Histamine receptor Ligand Histamine Phosphate Family 6 78
Histamine H3 receptor Ligand Cipralisant Family 36 70
Histamine H3 receptor and Histamine H4 receptor Ligand (r)-3-(... 26 80
Histamine H3 receptor Ligand GT-2016 Family 4 6
Histamine H2 receptor and Histamine H3 receptor ligand N,N'-bi... 2 1
Histamine H3 receptor ligand SureCN7961197 family 1 0
Histamine H2 receptor and Histamine H1 receptor ligand N-[N'-[... 1 2


External ID

Functional Category

Molecule Name

CFAMM00213371 CHEMBL98165 Bioactive SureCN7971153
CFAMM00213358 CHEMBL150701 Bioactive 4-[2-(1H-imidazol-5-yl)ethyl]piperidine
CFAMM00213368 CHEMBL317325 Bioactive 1-cyclohexyl-2-[4-(1H-imidazol-5-yl)butyl]guanidine
CFAMM00213375 CHEMBL1256702 Bioactive Thioperamide maleate
CFAMM00213366 DNC001435 Investigative Drug Thioperamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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