CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID570
Family Name Inosine-5'-monophosphate dehydrogenase Inhibitor VX-148 Family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00213673 Functional Category Investigative Drug
Superfamily Fatty-acid amide hydrolase 1 and Inosine-5'-monophosphate dehydrogenase Binder Superfamily
Class Class 336

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Neostigmine Family 4 76
Glucose-6-phosphate 1-dehydrogenase Inhibitor Metazamide Family 9 69
Bifunctional epoxide hydrolase 2 Inhibitor 1-adamantan-1-yl-3-... 12 44
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
Fatty-acid amide hydrolase 1 Inhibitor Phenmedipham Family 2 5
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
Transient receptor potential cation channel subfamily V member... 3 15
Gastrin/cholecystokinin type B receptor ligand 1-[3-[[2-(3-met... 2 12
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-088O2I family 3 3
Gonadotropin-releasing hormone receptor ligand SureCN5756131 f... 5 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00213674 CHEMBL118988 Bioactive [(2R)-1-cyanobutan-2-yl] N-[[3-[(4-cyano-3-methoxyphenyl)carbamoylamino]phenyl]methyl]carbamate
CFAMM00213673 DNC001506 Investigative Drug VX-148

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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