CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID575
Family Name Chymase Inhibitor Y-40613 Family
No. of Seeds 11 No. of Other Members 56
Family Centroid CFAMM00213852 Functional Category Investigative Drug
Superfamily Chymase Inhibitor Y-40613 Superfamily
Class Class 828

Cousin Family NamesSeedsMembers
Substance-P receptor Ligand R 673 Family 2 127
C-C chemokine receptor type 2 and C-C motif chemokine 2 Ligand... 3 52
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Melatonin receptor type 1B Ligand N-(3-benzooxazol-7-yl-propyl... 26 101
Neutrophil elastase Inhibitor Cbz-val-pro-val-(2-benzoxazole) ... 32 64
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 1 4
Fatty-acid amide hydrolase 1 Inhibitor 3-(benzo[d]oxazol-2-yl)... 1 6
Muscarinic acetylcholine receptor M3 ligand [(3R)-1-[3-(1,3-be... 3 2
Neutrophil elastase inhibitor 1-N-[(2S)-1-[(2S)-2-[[(2S)-1-(1,... 7 1
Neutrophil elastase inhibitor methyl 2-[(2S)-2-[[(2S)-1-[(2S)-... 5 0
Neutrophil elastase inhibitor methyl 2-[(2S)-3-methyl-2-[[(2S)... 2 0
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
Pol polyprotein inhibitor (2S)-4-(1,3-benzoxazol-2-ylmethyl)-1... 1 0
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 5 12
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 4 1
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 14 24
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 8
Cathepsin S inhibitor (2S,4R)-4-(benzenesulfonyl)-N-[1-(1,3-be... 4 0
Cathepsin S inhibitor (2S,4R)-4-(benzenesulfonyl)-N-[1-(1,3-be... 4 0
Coagulation factor X and Plasma kallikrein inhibitor (2R)-N-[2... 1 0
Neutrophil elastase inhibitor methyl 2-[(2S)-2-[[(2S)-1-[(2S)-... 3 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-2... 1 2
Neutrophil elastase inhibitor 2-[4-[2-[[(2S)-1-[(2S)-2-[[(2S)-... 1 0
Cathepsin S and Cathepsin L1 inhibitor (2S)-2-(1,3-benzoxazol-... 1 9


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00213825 CHEMBL402185 Bioactive methyl 2-[(2S)-2-[[2-[5-amino-2-(3-methoxyphenyl)-6-oxopyrimidin-1-yl]acetyl]amino]-3-phenylpropanoyl]-1,3-benzoxazole-5-carboxylate
CFAMM00213854 CHEMBL26285 Bioactive SureCN5622046
CFAMM00213817 CHEMBL256270 Bioactive methyl 2-[(2S)-2-[[2-(5-amino-6-oxo-2-phenylpyrimidin-1-yl)acetyl]amino]-3-phenylpropanoyl]-1,3-benzoxazole-5-carboxylate
CFAMM00213844 CHEMBL26297 Bioactive SureCN8059762
CFAMM00213823 CHEMBL111029 Bioactive methyl 2-[(2S)-3-methyl-2-[[(2S)-1-[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]pyrrolidine-2-carbonyl]amino]butanoyl]-1,3-benzoxazole-5-carboxylate
CFAMM00213836 CHEMBL131580 Bioactive amino 2-[(2S)-3-methyl-2-[[(2S)-1-[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]pyrrolidine-2-carbonyl]amino]butanoyl]-1,3-benzoxazole-5-carboxylate
CFAMM00213828 CHEMBL26127 Bioactive SureCN8060543
CFAMM00213794 CHEMBL107936 Bioactive methyl 2-[(2S)-2-[[(2S)-1-[(2S)-2-[(4-methoxybenzoyl)amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoyl]-1,3-benzoxazole-5-carboxylate
CFAMM00213826 CHEMBL108622 Bioactive methyl 2-[(2S)-3-methyl-2-[[(2S)-1-[(2S)-3-methyl-2-(phenoxycarbonylamino)butanoyl]pyrrolidine-2-carbonyl]amino]butanoyl]-1,3-benzoxazole-5-carboxylate
CFAMM00213861 CHEMBL1237168 Bioactive 2-[(2S)-3-methyl-2-[[(2S)-1-[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]pyrrolidine-2-carbonyl]amino]butanoyl]-1,3-benzoxazole-5-carboxylic acid
CFAMM00213852 DNC001522 Investigative Drug Y-40613

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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