CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Arachidonate 5-lipoxygenase Inhibitor ZM-230487 Family
No. of Seeds 3 No. of Other Members 23
Family Centroid CFAMM00213945 Functional Category Investigative Drug
Superfamily Arachidonate 5-lipoxygenase Inhibitor ZM-230487 Superfamily
Class Class 1389

Cousin Family NamesSeedsMembers
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Amyloid beta A4 protein Inhibitor 6-iodo-4'-methylaminoflavone... 3 33
Mitogen-activated protein kinase 14 inhibitor AGN-PC-044QVV fa... 4 2
Arachidonate 5-lipoxygenase inhibitor SureCN7477650 family 1 0
Arachidonate 5-lipoxygenase inhibitor SureCN9027452 family 1 0


External ID

Functional Category

Molecule Name

CFAMM00213937 CHEMBL283559 Bioactive methyl (2R)-2-[3-fluoro-5-[(1-methyl-2-oxoquinolin-6-yl)methoxy]phenyl]-2-methoxybutanoate
CFAMM00213929 DNC010936 Investigative Drug ZD-2138
CFAMM00213945 DNC001541 Investigative Drug ZM-230487

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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