CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID615
Family Name AP endonuclease APE1 Inhibitor 5-fluoro-1h-indole-2-carboxylic Acid Family
No. of Seeds 2 No. of Other Members 61
Family Centroid CFAMM00215675 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily Sodium channel Ligand GSK1014802 Superfamily
Class Class 247

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Dolasetron Family 12 171
Prostaglandin G/H synthase 2 Inhibitor Carprofen Family 1 5
Fibroblast growth factor receptor 1 and Aurora kinase B Inhibi... 4 51
Sodium channel Ligand GSK1014802 Family 4 92
Indeglitazar family 3 39
Substance-K receptor and Substance-P receptor Ligand L-732138 ... 8 147
Vascular endothelial growth factor receptor 1 Ligand Lycogarub... 6 292
Platelet-derived growth factor receptor alpha and Platelet-der... 4 54
Platelet-derived growth factor receptor alpha and Platelet-der... 2 13
Tyrosine-protein phosphatase non-receptor type 1 Ligand Cauler... 2 8
Lethal factor Inhibitor 3-(2,5-dimethyl-1h-pyrrol-1-yl)benzoic... 2 44
Serine/threonine-protein kinase Chk1 and Wee1-like protein kin... 2 101
Fatty acid-binding protein, adipocyte Inhibitor 1-benzyl-2,3-d... 1 8
Kinesin-like protein KIF11 Inhibitor Methyl 7-tert-butyl-9h-ca... 2 9
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 24 64
Tubulin beta chain Inhibitor Isopropyl 3-(phenylthio)-1h-indol... 1 7
5-hydroxytryptamine receptor 3A Ligand 3alpha-(1'-methyl-2'-in... 2 17
Cathepsin K and Cathepsin S inhibitor dipeptidyl nitrile, 16f ... 3 18
Glutamate receptor ionotropic, NMDA 1 ligand (3S)-3-[2-[4-(ami... 2 2
NS5B protein inhibitor AGN-PC-00A17Z family 1 23
Collagenase 3 and Matrix metalloproteinase-14 inhibitor 4-[[[5... 2 4
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 3 6
3-oxo-5-alpha-steroid 4-dehydrogenase 2 inhibitor 4-(benzyloxy... 1 10
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 3 9
Glutamate carboxypeptidase 2 inhibitor 1-[(3-carboxyphenyl)met... 4 11
Prelamin-A/C and Beta-lactamase inhibitor CHEMBL1340977 family 1 5
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 0
Glutamate receptor 4 and Glutamate receptor 2 ligand SureCN437... 4 12
Serine/threonine-protein kinase pim-3 inhibitor methyl 6-amino... 1 2
Indoles Metabolite 7-Hydroxyheptaphylline Family 4 0
Indoles Metabolite Mukeic acid Family 1 1
Amino Acids and Derivatives Metabolite Flazine Family 3 2
methyl 4-[(5Z)-5-(1H-indol-3-ylmethylidene)-4-oxo-2-sulfanylid... 1 0
3-(2-azaniumylethyl)-5-bromo-1H-indole-2-carboxylate NP 3-(2-a... 1 0
2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-2-ium-8-carboxylate N... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00215675 DNC002378 Investigative Drug 5-fluoro-1H-indole-2-carboxylic acid
CFAMM00215680 DNC009711 Investigative Drug 2-(ethoxycarbonyl)-1H-indole-5-carboxylic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27619 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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