CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID63
Family Name PF-3758309 family
No. of Seeds 1 No. of Other Members 8
Family Centroid CFAMM00177179 Functional Category Investigative Drug
Superfamily PF-3758309 Superfamily
Class Class 1378

Cousin Family NamesSeedsMembers
Tyrosine-protein kinase Lck and Aurora kinase B Inhibitor VX-6... 28 56
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Aurora kinase A Inhibitor ABT-348 Family 20 49
Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibi... 6 64
Prostaglandin G/H synthase 2 Inhibitor GW-637185X Family 27 48
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 22
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Mitogen-activated protein kinase 14 inhibitor 6-[3-amino-5-(2-... 4 9
5-hydroxytryptamine receptor 6 ligand AGN-PC-03P3TZ family 6 88
5-hydroxytryptamine receptor 6 ligand AGN-PC-031XQS family 1 1
Prothrombin and Histone-lysine N-methyltransferase 2A inhibito... 1 7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 2
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 1 11
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 2 18
Metabotropic glutamate receptor 4 and Potassium voltage-gated ... 2 15
Vascular endothelial growth factor receptor 1 and Vascular end... 4 0
3-phosphoinositide-dependent protein kinase 1 and MAP kinase-a... 1 5
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 12 7
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 6 1
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 3 6
Prostaglandin G/H synthase 2 inhibitor 4-N,4-N-diethyl-2-(4-me... 5 1
Epidermal growth factor receptor and Vascular endothelial grow... 2 1
Epidermal growth factor receptor and Vascular endothelial grow... 7 0
Epidermal growth factor receptor and Vascular endothelial grow... 3 1
Adenosine receptor A2a and Adenosine receptor A2b ligand SureC... 4 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00177179 DND000007 Investigative Drug PF-3758309

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27639 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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