CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Prostaglandin G/H synthase 1 Inhibitor (3-chloro-4-propoxy-phenyl)-acetic Acid Family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00216155 Functional Category Investigative Drug
Superfamily Prostaglandin G/H synthase 1 Inhibitor (3-chloro-4-propoxy-phenyl)-acetic Acid Superfamily
Class Class 1381

Cousin Family NamesSeedsMembers
Thyroid hormone receptor alpha ligand thyroid hormone analog L... 10 61
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Cyclooxygenase inhibitor salicylate derivative Aspirin family 3 234
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Solute carrier family 12 member 1 Inhibitor Ethacrynic Acid Fa... 3 42
Vitamin K epoxide reductase complex subunit 1 Inhibitor Warfar... 9 508
Eprotirome family 11 50
Phospholipase A2 Inhibitor P-anisic Acid Family 2 178
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Cytosolic phospholipase A2 Inhibitor 1,1,1-trifluoro-6-(4-hexy... 9 86
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Interleukin-8 Inhibitor 2-(2-(2-fluorophenoxy)phenyl)acetic Ac... 2 4
Peroxisome proliferator-activated receptor alpha and Peroxisom... 7 6
Peroxisome proliferator-activated receptor alpha ligand SureCN... 9 3
Peroxisome proliferator-activated receptor alpha ligand AGN-PC... 5 2
Free fatty acid receptor 1 ligand SureCN14018049 family 1 0
Free fatty acid receptor 1 ligand 3-[4-[2-[2-(cyanomethoxy)phe... 1 2
Peroxisome proliferator-activated receptor alpha and Peroxisom... 2 8
Phenylacetic Acid Derivatives Metabolite Guaicyl phenylacetate... 1 3
NP 3,5-dichloro-4-methoxybenzoate Family 1 4


External ID

Functional Category

Molecule Name

CFAMM00216155 DNC002448 Investigative Drug (3-Chloro-4-Propoxy-Phenyl)-Acetic Acid
CFAMM00216151 DNC009850 Investigative Drug 2-(2-(2-chlorophenoxy)phenyl)acetic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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