CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Prothrombin Inhibitor 4-[3-(4-chlorophenyl)-1h-pyrazol-5-yl]piperidine Family
No. of Seeds 7 No. of Other Members 39
Family Centroid CFAMM00216592 Functional Category Investigative Drug
Superfamily Prothrombin Inhibitor 4-[3-(4-chlorophenyl)-1h-pyrazol-5-yl]piperidine Superfamily
Class Class 1717

Cousin Family NamesSeedsMembers
NKP-1339 family 3 7
D(4) dopamine receptor Ligand Fauc 113 Family 14 96
Tyrosine-protein kinase JAK2 Inhibitor 5-phenyl-1h-indazol-3-a... 1 7
Acetylcholinesterase Inhibitor 3-[2-(1-benzyl-piperidin-4-yl)-... 2 9
Vascular endothelial growth factor receptor 2 Ligand 3-phenyl-... 2 1
Calcium-activated potassium channel subunit alpha-1 Ligand 1-(... 3 3
Kappa-type opioid receptor and Potassium voltage-gated channel... 10 10
Cytochrome P450 3A4 Inhibitor 5-(2-phenethylpiperazin-1-yl)-1h... 12 35
Corticotropin-releasing factor receptor 1 ligand AGN-PC-074YT9... 28 20
Sodium-dependent serotonin transporter and Sodium-dependent no... 14 6
Sodium-dependent serotonin transporter and Sodium-dependent no... 1 0
Aurora kinase B and Aurora kinase A inhibitor SureCN5594082 fa... 2 3
Lethal(3)malignant brain tumor-like protein 1 and 15-hydroxypr... 1 1
Microtubule-associated protein tau inhibitor CHEMBL1544706 family 1 0
Serine/threonine-protein kinase Chk1 inhibitor N-[[3-(4-fluoro... 1 4


External ID

Functional Category

Molecule Name

CFAMM00216565 CHEMBL78933 Bioactive SureCN1388694
CFAMM00216555 CHEMBL76090 Bioactive SureCN1388458
CFAMM00216579 CHEMBL77744 Bioactive 4-(3-cyclohexyl-1H-pyrazol-5-yl)-1-(2-phenylethyl)piperidine
CFAMM00216585 CHEMBL309901 Bioactive SureCN1388702
CFAMM00216552 CHEMBL61079 Bioactive SureCN1388420
CFAMM00216597 CHEMBL6416 Bioactive SureCN1388360
CFAMM00216592 DNC002478 Investigative Drug 4-[3-(4-CHLOROPHENYL)-1H-PYRAZOL-5-YL]PIPERIDINE

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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