CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID673
Family Name cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Gamma-glutamyl[s-(2-iodobenzyl)cysteinyl]glycine Family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00216957 Functional Category Investigative Drug
Superfamily cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Gamma-glutamyl[s-(2-iodobenzyl)cysteinyl]glycine Superfamily
Class Class 1736

Cousin Family NamesSeedsMembers
Penicillin binding protein inhibitor β-lactam aminopenicillin ... 12 359
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 16 374
Angiotensin-converting enzyme Inhibitor Spirapril Family 17 86
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 7 54
Bacterial outer membrane Inhibitor Polymyxin B Family 17 181
Angiotensin-converting enzyme and Neprilysin Inhibitor M100,24... 18 60
Ezatiostat family 1 4
Neprilysin Inhibitor Thiorphan Family 41 68
Neuromedin-K receptor Ligand Senktide Family 15 22
Beta-secretase 1 Inhibitor Glu-leu-asp-leu-(choh-ch2)-ala-ala-... 15 11
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 3 21
Histone deacetylase 1 and Histone deacetylase 4 Inhibitor Azum... 3 10
Disks large homolog 4 Inhibitor N-(3,4-difluorophenyl)propyl-e... 3 0
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-154957 Family 2 3
Genome polyprotein Inhibitor Acasp-glu-dif-glu-cha-cys Family 13 17
Genome polyprotein Inhibitor Acasp-glu-met-glu-cha-cys Family 3 6
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 2
Angiotensin-converting enzyme and Neprilysin inhibitor (5R,7S)... 1 0
Caspase-3 and Caspase-7 inhibitor valine aspartyl ketone 16 fa... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00216959 DNC014082 Investigative Drug S-p-bromobenzyl glutatione
CFAMM00216957 DNC002537 Investigative Drug Gamma-Glutamyl[S-(2-Iodobenzyl)Cysteinyl]Glycine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

42686 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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