CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Purine nucleoside phosphorylase Inhibitor 9-(5,5-difluoro-5-phosphonopentyl)guanine Family
No. of Seeds 1 No. of Other Members 16
Family Centroid CFAMM00217070 Functional Category Investigative Drug
Superfamily Purine nucleoside phosphorylase and Hypoxanthine-guanine-xanthine phosphoribosyltransferase Binder Superfamily 2
Class Class 150

Cousin Family NamesSeedsMembers
cAMP-specific 3',5'-cyclic phosphodiesterase 4A inhibitor xant... 18 210
Tumor necrosis factor inhibitor xanthine derivative Pentoxifyl... 5 69
xanthine alkaloid Theobromine family 6 10
DNA polymerase inhibitor guanosine analog Aciclovir Family 4 41
Hypoxanthine-guanine-xanthine phosphoribosyltransferase Inhibi... 3 7
Purine nucleoside phosphorylase inhibitor [(3R,4S)-3-(2-amino-... 1 0


External ID

Functional Category

Molecule Name

CFAMM00217070 DNC002562 Investigative Drug 9-(5,5-Difluoro-5-Phosphonopentyl)Guanine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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