CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Eprotirome family
No. of Seeds 11 No. of Other Members 50
Family Centroid CFAMM00178251 Functional Category Investigative Drug
Superfamily Eprotirome Superfamily
Class Class 1381

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Solute carrier family 12 member 1 Inhibitor Ethacrynic Acid Fa... 3 42
Prostaglandin G/H synthase 1 Inhibitor (3-chloro-4-propoxy-phe... 2 10
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Oestrogen receptor and Estrogen receptor beta Ligand 7-chloro-... 2 27
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Peroxisome proliferator-activated receptor alpha and Peroxisom... 4 28
Peroxisome proliferator-activated receptor alpha and Peroxisom... 7 6
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 4 3
Peroxisome proliferator-activated receptor alpha ligand SureCN... 9 3
Peroxisome proliferator-activated receptor alpha ligand AGN-PC... 5 2
Peroxisome proliferator-activated receptor delta and Peroxisom... 4 2
Transthyretin inhibitor AGN-PC-046XQV family 1 6
Free fatty acid receptor 1 ligand SureCN14018049 family 1 0


External ID

Functional Category

Molecule Name

CFAMM00178277 CHEMBL418432 Bioactive SureCN7069853
CFAMM00178290 CHEMBL236438 Bioactive 4-hydroxy thyromimetic, 9j
CFAMM00178253 CHEMBL424685 Bioactive (2S)-2-[[4-[3-(2-chloro-4-cyclohexylphenoxy)propoxy]phenyl]methyl]-2-methylbutanoic acid
CFAMM00178282 CHEMBL251456 Bioactive SureCN2786702
CFAMM00178287 CHEMBL393489 Bioactive 4-hydroxy thyromimetic, 9f
CFAMM00178267 CHEMBL396304 Bioactive 4-hydroxy thyromimetic, 9s
CFAMM00178292 CHEMBL442243 Bioactive 4-hydroxy thyromimetic, 9c
CFAMM00178285 CHEMBL442280 Bioactive 4-hydroxy thyromimetic, 9b
CFAMM00178291 CHEMBL236436 Bioactive 4-hydroxy thyromimetic, 9i
CFAMM00178297 CHEMBL235788 Bioactive 4-hydroxy thyromimetic, 9a
CFAMM00178251 DND000063 Investigative Drug Eprotirome

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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