CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID759
Family Name Proto-oncogene tyrosine-protein kinase Src Inhibitor Malonic Acid Family
No. of Seeds 1 No. of Other Members 34
Family Centroid CFAMM00218346 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 Binder Superfamily 3
Class Class 426

Cousin Family NamesSeedsMembers
Cyclooxygenase inhibitor salicylate derivative Aspirin family 3 234
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
Vitamin K epoxide reductase complex subunit 1 Inhibitor Warfar... 9 508
Vitamin K-dependent gamma-carboxylase Inhibitor Anisindione Fa... 3 243
Ipriflavone family 62 2480
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Phospholipase A2 Inhibitor P-anisic Acid Family 2 178
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Platelet-activating factor receptor Ligand L-652731 Family 5 116
Cytosolic phospholipase A2 Inhibitor 1,1,1-trifluoro-6-(4-hexy... 9 86
Coagulation factor X and Prothrombin Inhibitor 3-chlorophenyl ... 2 12
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 127
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Ethox... 12 80
Thyroid hormone receptor beta Ligand 2-hexylphenyl Acrylate Fa... 4 83
Kappa-type opioid receptor Ligand Anisocoumarin H Family 3 5
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 2 12
Aromatase Inhibitor NSC-122427 Family 1 0
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 6-meth... 2 36
Amine oxidase [flavin-containing] B Inhibitor 3-(4-methoxyphen... 3 29
Indoleamine 2,3-dioxygenase 1 Inhibitor 4-methoxybenzenemethan... 2 26
Prostaglandin G/H synthase 1 Inhibitor Acetic Acid 2-heptylsel... 1 14
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 2-(3-c... 5 72
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Androgen receptor Ligand Palodesangren E Family 12 43
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 3 27
Amine oxidase [flavin-containing] B Inhibitor Methyl Piperate ... 1 19
Histone deacetylase 2 and Histone deacetylase 8 inhibitor 2-hy... 1 0
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 2 10
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor propan... 3 5
Benzyloxycarbonyls Metabolite 4-Methoxybenzyl formate Family 1 7
Phenylacetic Acid Derivatives Metabolite Guaicyl phenylacetate... 1 3
Putative NP ZINC04012191 Family 2 2
2-methyl-2H-chromene-3-carbaldehyde NP 2-methyl-2h-chromene-3-... 2 1
2-[(3,4-dimethoxyphenyl)methyl]propanedioate NP 4aji Family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00218346 DNC002759 Investigative Drug Malonic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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