CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID761
Family Name Proto-oncogene tyrosine-protein kinase Src Inhibitor RU85053 Family
No. of Seeds 6 No. of Other Members 8
Family Centroid CFAMM00218443 Functional Category Investigative Drug
Superfamily Proto-oncogene tyrosine-protein kinase Src Inhibitor RU85053 Superfamily
Class Class 923

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Quinapril Family 3 105
Microsomal triglyceride transfer protein large subunit Inhibit... 15 208
Farnesyltransferase beta subunit, putative and Protein farnesy... 24 82
Plasmepsin-2 Inhibitor PS-222036 Family 12 134
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 6 24
Delta-type opioid receptor Ligand H-cxp-ala-gly-phe-leu-oh Family 1 8
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Inhibit... 5 23
Cholecystokinin receptor type A Ligand CR-1795 Family 19 41
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 3 9
Cathepsin B and Cathepsin L1 inhibitor 3-[[(2R)-2-cyano-2-[[(2... 3 4
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor N-[4-... 30 10
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 13 22
Dipeptidyl peptidase 4 inhibitor 3-[2-[(4R,5R)-5-amino-2-oxo-4... 1 4
Cathepsin B and Cathepsin L1 inhibitor SureCN14345745 family 2 0
Bifunctional epoxide hydrolase 2 inhibitor SureCN4203288 family 2 2
Delta-type opioid receptor and Kappa-type opioid receptor liga... 3 4
Neutrophil elastase inhibitor 3-[[(2S)-3-methyl-1-oxo-1-[2-[(1... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00218449 CHEMBL421518 Bioactive RU85052
CFAMM00218440 CHEMBL305856 Bioactive 2-[4-[(2R)-2-acetamido-3-oxo-3-[[(3S)-2-oxo-1-[(4-phenylphenyl)methyl]azepan-3-yl]amino]propyl]-2-methoxycarbonylphenyl]propanedioic acid
CFAMM00218446 DNC002765 Investigative Drug RU82129
CFAMM00218445 DNC002761 Investigative Drug RU90395
CFAMM00218443 DNC002774 Investigative Drug RU85053
CFAMM00218450 DNC002768 Investigative Drug RU82197

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27264 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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