CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID768
Family Name Proto-oncogene tyrosine-protein kinase Src Inhibitor ISO24 Family
No. of Seeds 3 No. of Other Members 9
Family Centroid CFAMM00218508 Functional Category Investigative Drug
Superfamily Proto-oncogene tyrosine-protein kinase Src Inhibitor ISO24 Superfamily
Class Class 1793

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(3) dopamine receptor ligand indol... 4 123
Sodium channel Ligand xylidine derivative Mepivacaine Family 10 114
Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
Cholesterol side-chain cleavage enzyme, mitochondrial and Arom... 9 26
Histone deacetylase 1 Inhibitor Vorinostat Family 26 138
Motilin receptor Ligand GSK962040 Family 30 457
Pan-DAC Inhibitor AR-42 Family 21 153
Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Octanoic... 4 14
Transient receptor potential cation channel subfamily V member... 6 33
Thyroid hormone receptor alpha and Thyroid hormone receptor be... 1 16
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Leukotriene A-4 hydrolase Inhibitor N5-[4-benzylphenyl]-l-glut... 2 1
Farnesyl pyrophosphate synthase Inhibitor (biphenyl-3-ylamino)... 1 3
Sphingosine kinase 2 Inhibitor (r)-2-amino-4-hydroxy-n-(4-octy... 3 9
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
Tyrosinase Inhibitor S-2-(o-toluidino)-2-oxoethyl Carbamothioa... 1 1
DNA topoisomerase Inhibitor 6-p-tolylamino-1h-pyrimidine-2,4-d... 3 17
Prothrombin and Plasminogen inhibitor [(1R)-5-amino-1-[[2-[N-(... 1 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor [(2S)-2... 9 6
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 2 7
Ectonucleotide pyrophosphatase/phosphodiesterase family member... 1 0
Sphingosine 1-phosphate receptor 5 and Sphingosine 1-phosphate... 1 0
Acyl-CoA:cholesterol acyltransferase inhibitor N-[2,6-di(propa... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00218516 CHEMBL1818144 Bioactive cyclohexylazanium;hydroxy-[[4-(tetradecanoylamino)phenyl]methyl]phosphinate
CFAMM00218514 CHEMBL1818146 Bioactive cyclohexylazanium;[fluoro-[4-(tetradecanoylamino)phenyl]methyl]-hydroxyphosphinate
CFAMM00218508 DNC002773 Investigative Drug ISO24

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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