CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID774
Family Name Urokinase-type plasminogen activator Inhibitor 6-(n-phenylcarbamyl)-2-naphthalenecarboxamidine Family
No. of Seeds 2 No. of Other Members 11
Family Centroid CFAMM00218705 Functional Category Investigative Drug
Superfamily Urokinase-type plasminogen activator Inhibitor 6-(n-phenylcarbamyl)-2-naphthalenecarboxamidine Superfamily
Class Class 1489

Cousin Family NamesSeedsMembers
5-alpha reductase inhibitor azasteroid derivative Dutasteride ... 36 124
Retinoic acid receptor alpha Ligand Tamibarotene Family 5 95
Microsomal triglyceride transfer protein large subunit Inhibit... 15 208
Motilin receptor Ligand GSK962040 Family 30 457
Histone deacetylase 1 Inhibitor AN-9 Family 31 282
Pan-DAC Inhibitor AR-42 Family 21 153
Amonafide family 3 35
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Delta-type opioid receptor Ligand Sb 227122 Family 7 5
Vasopressin V2 receptor Ligand FR161282 Family 17 83
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Poly [ADP-ribose] polymerase 1 Inhibitor 8-amino-6h,11h-indeno... 3 9
Transient receptor potential cation channel subfamily V member... 6 33
Poly [ADP-ribose] polymerase 1 Inhibitor 3-morpholin-4-ylmethy... 1 2
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 41 24
Integrin alpha-2 and Integrin beta-3 Inhibitor 3-(3-(carbamoyl... 7 13
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 3 26
Beta-secretase 1 and Cathepsin D Inhibitor GRL-7234 Family 17 148
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 7 13
Cannabinoid receptor 2 Ligand N1-(4-bromophenyl)-n2,n2-dipenty... 4 21
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 12 4
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
5-hydroxytryptamine receptor 2A Ligand N-(1-(4-nitrobenzyl)pip... 4 6
5-hydroxytryptamine receptor 2A Ligand N-(1-(3-bromobenzyl)pip... 6 10
Dihydroorotate dehydrogenase Inhibitor N-(4-bromo-2-methylphen... 1 3
Acetylcholinesterase inhibitor AGN-PC-07ZFTY family 1 0
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07ZFJZ family 1 3
3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... 4 8
Prothrombin and Cationic trypsin inhibitor (2S)-1-[(2R)-2-anil... 1 2
Integrin beta-3 and Integrin alpha-IIb inhibitor 2-[7-[[4-(N'-... 7 15
C-C chemokine receptor type 3 ligand 4-[(3-acetylphenyl)carbam... 3 4
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7345980... 4 6
C-C chemokine receptor type 3 ligand SureCN6703027 family 2 1
Apolipoprotein B-100 and Microsomal triglyceride transfer prot... 10 0
Apolipoprotein B-100 and Microsomal triglyceride transfer prot... 6 5
D(3) dopamine receptor and Alpha-1B adrenergic receptor ligand... 11 8
Prelamin-A/C inhibitor CHEMBL1547148 family 1 8
Coagulation factor X and Trypsin-1 inhibitor SureCN6161266 family 2 28
Coagulation factor X and Trypsin-1 inhibitor 3-carbamimidoyl-N... 1 1
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 4 0
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075BLN ... 2 1
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 0
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 8 1
Follicle-stimulating hormone receptor ligand AGN-PC-005HER family 5 2
Delta-type opioid receptor and Potassium voltage-gated channel... 3 2
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 1 0
Transient receptor potential cation channel subfamily V member... 1 1
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 3 0
Microsomal triglyceride transfer protein large subunit inhibit... 8 1
P2X purinoceptor 7 inhibitor 2-[3-fluoro-4-(trifluoromethyl)ph... 3 0
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 4 0
Protease and Replicase polyprotein 1a inhibitor AC1LALLS family 1 0
Vascular endothelial growth factor receptor 2 ligand isoindoli... 1 0
Phospholipase D1 and Phospholipase D2 inhibitor N-[(2S)-1-[4-(... 3 5
Muscarinic acetylcholine receptor M2 ligand AGN-PC-073RRB family 2 1
Integrin beta-3 and Integrin alpha-IIb inhibitor AGN-PC-0BOW0P... 1 0
Fatty-acid amide hydrolase 1 inhibitor [(E)-1-[3-(3-carbamoylp... 1 0
Progesterone receptor ligand AGN-PC-00PB7N family 2 1
Acenes Metabolite C.I. Pigment Red 149 Family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00218705 DNC002788 Investigative Drug 6-(N-Phenylcarbamyl)-2-Naphthalenecarboxamidine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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