CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID777
Family Name Urokinase-type plasminogen activator Inhibitor N-(1-adamantyl)-n'-(4-guanidinobenzyl)urea Family
No. of Seeds 2 No. of Other Members 15
Family Centroid CFAMM00218731 Functional Category Investigative Drug
Superfamily Urokinase-type plasminogen activator Inhibitor N-(1-adamantyl)-n'-(4-guanidinobenzyl)urea Superfamily
Class Class 1799

Cousin Family NamesSeedsMembers
Sodium channel Ligand iminostilbene derivative (tricyclic stru... 2 46
NMDA receptor Ligand Aptiganel Hcl Family 2 82
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 14 78
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-[2-(... 5 72
Androgen receptor Ligand YM-175735 Family 30 129
Kinesin-like protein KIF11 Inhibitor N-(4'-bromo-3,3'-difluoro... 2 0
Kinesin-like protein KIF11 Inhibitor N-[4'-(trifluoromethyl)-4... 7 134
Cholinesterase Inhibitor N-p-tolyl-1'h-phenothiazine-1'-carbox... 4 1
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
DNA topoisomerase Inhibitor 6-p-tolylamino-1h-pyrimidine-2,4-d... 3 17
DNA topoisomerase Inhibitor 6-(naphthalen-2-ylamino)-1h-pyrimi... 2 1
Bifunctional epoxide hydrolase 2 inhibitor 1-(2-adamantyl)-3-(... 2 4
Inosine-5'-monophosphate dehydrogenase inhibitor 1-(3,4-dichlo... 1 1
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor 1-(3,5... 2 0
Sigma non-opioid intracellular receptor 1 and Glutamate recept... 3 2
Sigma non-opioid intracellular receptor 1 and Glutamate recept... 1 0
Sterol O-acyltransferase 1 inhibitor SureCN7565101 family 2 10
Acyl-CoA:cholesterol acyltransferase inhibitor 1-[2,6-di(propa... 7 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00218731 DNC002792 Investigative Drug N-(1-Adamantyl)-N'-(4-Guanidinobenzyl)Urea
CFAMM00218735 DNC009107 Investigative Drug 1-Adamantan-1-yl-3-phenyl-urea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27075 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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