CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID833
Family Name Cyclin-dependent kinase 2 Inhibitor N-(5-cyclopropyl-1h-pyrazol-3-yl)benzamide Family
No. of Seeds 6 No. of Other Members 62
Family Centroid CFAMM00219438 Functional Category Investigative Drug
Superfamily Cyclin-dependent kinase 2 and Glycogen synthase kinase-3 beta Binder Superfamily
Class Class 827

Cousin Family NamesSeedsMembers
Macrophage colony-stimulating factor 1 Inhibitor ABT-869 Family 8 56
Aurora kinase B and Aurora kinase A Inhibitor PHA-739358 Family 6 29
Aurora kinase B and Aurora kinase C Inhibitor PHA-680632 Family 5 72
Glycogen synthase kinase-3 beta Inhibitor N-(6-chloro-5-p-toly... 5 9
Glycogen synthase kinase-3 beta Inhibitor N-(6-(3-hydroxypheny... 2 4
Glycogen synthase kinase-3 beta Inhibitor (e)-n-(6-(prop-1-eny... 3 0
Glycogen synthase kinase-3 beta Inhibitor N-(6-(thiophen-3-yl)... 4 3
Metabotropic glutamate receptor 5 Ligand N-(1,3-diphenyl-1h-py... 6 37
Poly [ADP-ribose] polymerase 1 inhibitor 2-[2-[4-(1H-indazol-3... 1 0
Aurora kinase A inhibitor SureCN3894803 family 5 8
Serine/threonine-protein kinase 17A and Myosin light chain kin... 3 7
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor AGN-PC-0A9SI... 4 0
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 2 6
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 4 20
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 2 18
Cell division cycle 7-related protein kinase and Casein kinase... 2 0
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 1 0
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 4 0
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 10 9
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 4 4
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor 1-[6,6-dimet... 1 0
Aurora kinase A and Aurora kinase B inhibitor SureCN4059106 fa... 1 0
Neuropeptide Y receptor type 5 ligand 3-[3-[2-[[5-(4-chlorophe... 1 0
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor 3-Aminopyraz... 1 0
Aurora kinase A and Tyrosine-protein kinase SYK inhibitor AGN-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00219407 CHEMBL112433 Bioactive 3-Phenylacetamidoaminopyrazole deriv. 39
CFAMM00219426 CHEMBL114718 Bioactive 3-Phenylacetamidoaminopyrazole deriv. 36
CFAMM00219386 CHEMBL489477 Bioactive N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-(3-fluoro-4-phenylphenyl)acetamide
CFAMM00219439 CHEMBL114790 Bioactive 3-Phenylacetamidoaminopyrazole deriv. 37
CFAMM00219444 CHEMBL490480 Bioactive N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-(3-methyl-4-phenylphenyl)acetamide
CFAMM00219438 DNC002910 Investigative Drug N-(5-Cyclopropyl-1h-Pyrazol-3-Yl)Benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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