CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID836
Family Name Cyclin-dependent kinase 2 Inhibitor 2-anilino-6-cyclohexylmethoxypurine Family
No. of Seeds 4 No. of Other Members 13
Family Centroid CFAMM00219467 Functional Category Investigative Drug
Superfamily Cyclin-dependent kinase 2 and Methylated-DNA--protein-cysteine methyltransferase Binder Superfamily
Class Class 1696

Cousin Family NamesSeedsMembers
Cyclin-dependent kinase 2 Inhibitor 6-cyclohexylmethyloxy-2-(4... 2 11
Methylated-DNA--protein-cysteine methyltransferase Inhibitor 6... 4 5
Adenosine receptor A3 and Dual specificity mitogen-activated p... 5 27
Adenosine receptor A1 and Adenosine receptor A3 Ligand 2-(4-me... 3 23
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SK&F-96... 5 83
Cathepsin K and Cathepsin L1 inhibitor CHEBI:43424 family 2 0
Interleukin-1 receptor-associated kinase 4 and Interleukin-1 r... 4 0
Dual specificity protein kinase TTK inhibitor 4-[[2-(2-methyl-... 1 0
Dual specificity protein kinase TTK inhibitor 6-N-cyclohexyl-2... 12 2
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor [4-amino-6-(... 3 2
Methylated-DNA--protein-cysteine methyltransferase inhibitor A... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00219465 CHEMBL434217 Bioactive O6-Cyclohexylmethylguanine deriv. 28
CFAMM00219469 DNC003263 Investigative Drug 6-CYCLOHEXYLMETHOXY-2-(3'-CHLOROANILINO) PURINE
CFAMM00219467 DNC002916 Investigative Drug 2-ANILINO-6-CYCLOHEXYLMETHOXYPURINE
CFAMM00219457 DNC006296 Investigative Drug NU-6102

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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