CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID857
Family Name Peptide deformylase, mitochondrial Inhibitor 5-chloryl-2,4,6-quinazolinetriamine Family
No. of Seeds 2 No. of Other Members 6
Family Centroid CFAMM00220209 Functional Category Investigative Drug
Superfamily Epidermal growth factor receptor and Peptide deformylase, mitochondrial Binder Superfamily
Class Class 343

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Pyrimethamine Family 10 145
Transient receptor potential cation channel subfamily V member... 15 457
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 8 55
5-hydroxytryptamine receptor 2B Ligand MT-500 Family 8 39
Epidermal growth factor receptor and Receptor tyrosine-protein... 11 138
Peptide deformylase, mitochondrial Inhibitor 5-phenethyl-quina... 5 14
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Epidermal growth factor receptor Ligand N*4*-(3-bromo-phenyl)-... 7 11
Epidermal growth factor receptor Ligand (3-bromo-phenyl)-quina... 7 5
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Epidermal growth factor receptor Ligand N4-(3-chlorophenyl)qui... 7 39
Cathepsin K Inhibitor 4-phenyl-6-propylpyrimidine-2-carbonitri... 6 10
Oestrogen receptor Ligand 4-benzyl-2,6-diisobutylamino-pyrimid... 5 37
Sodium-dependent serotonin transporter Inhibitor 6-chloro-2-pi... 5 35
Metabotropic glutamate receptor 5 Ligand 2-methyl-7-m-tolyl-1,... 5 2
Epidermal growth factor receptor ligand N-[4-(3-chloro-4-fluor... 8 4
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
Epidermal growth factor receptor and Receptor tyrosine-protein... 3 0
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 1 0
Dihydrofolate reductase inhibitor N-(2,4-diamino-5-methylquina... 2 0
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 1 2
1-acyl-sn-glycerol-3-phosphate acyltransferase beta inhibitor ... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00220207 CHEMBL355093 Bioactive 6-N-[(3-bromophenyl)methyl]-5-chloroquinazoline-2,4,6-triamine
CFAMM00220209 DNC002965 Investigative Drug 5-Chloryl-2,4,6-Quinazolinetriamine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26190 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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