CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID862
Family Name Nicotinate-nucleotide pyrophosphorylase [carboxylating] Inhibitor Phthalic Acid Family
No. of Seeds 2 No. of Other Members 119
Family Centroid CFAMM00220533 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily Nicotinate-nucleotide pyrophosphorylase [carboxylating] Inhibitor Phthalic Acid Superfamily
Class Class 1012

Cousin Family NamesSeedsMembers
Retinoid X receptor Ligand Bexarotene Family 7 492
DNA topoisomerase 1 Inhibitor Beta-lapachone Family 3 66
Carbonic anhydrase 2 Inhibitor 4-(hydroxymercury)benzoic Acid ... 7 97
Beta-lactamase Inhibitor 4-carboxyphenylboronic Acid Family 1 1
C-X-C chemokine receptor type 1 and C-X-C chemokine receptor t... 2 53
Liver carboxylesterase 1 Inhibitor 2,2-dimethoxy-1,2-diphenyl-... 1 16
Glutamate carboxypeptidase 2 Inhibitor 2-(3-carboxybenzyl)succ... 2 7
Glutamate carboxypeptidase 2 Inhibitor 3-(2-carboxy-6-mercapto... 9 4
Gamma-secretase subunit APH-1B and Presenilin-1 Inhibitor (5r,... 3 9
Neutrophil elastase Inhibitor 3,4-dichloroisocoumarin Family 1 5
Indoleamine 2,3-dioxygenase 1 Inhibitor 2-methoxy-1,4-naphthoq... 1 3
Protein kinase C delta type and Protein kinase C alpha type In... 4 105
Fatty-acid amide hydrolase 1 Inhibitor 3-(ethoxycarbonyl)pheny... 2 69
Cellular tumor antigen p53 and Thyrotropin receptor ligand CHE... 1 19
Protein kinase C alpha type inhibitor [(4E)-4-[(4-fluorophenyl... 4 66
Protein kinase C delta type and Protein kinase C beta type inh... 3 9
RAC-alpha serine/threonine-protein kinase inhibitor CHEMBL4754... 2 17
Arachidonate 15-lipoxygenase inhibitor SureCN9469035 family 6 40
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 10
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 18
Aromatase inhibitor [(8R,9S,10R,13S,14S)-10,13-dimethyl-17-oxo... 2 10
Sodium-dependent dopamine transporter and Sodium-dependent nor... 1 0
Benzyloxycarbonyls Metabolite Benzyl acetate Family 5 53
Epoxides Metabolite Phenylmethylglycidic ester Family 2 17
Aromatic Homomonocyclic Compounds Metabolite Dimethylbenzyl ca... 2 11
[(1S,2S,5R)-2-hydroxy-2-methyl-5-prop-1-en-2-ylcyclohexyl] ben... 1 2
3-methyl-1-oxo-4H-isochromene-3-carboxylate NP Methyl 3-methyl... 4 1
Putative NP ZINC00277961 Family 3 1
4-hydroxy-2-(4-methoxycarbonylphenyl)-4-methyl-6-oxocyclohexan... 15 2
3-(4-hydroxy-6-methyl-2-oxopyran-3-yl)-3H-2-benzofuran-1-one N... 2 2
carboxylate NP ZINC04026424 Family 3 7
methylbenzoate NP 7-oxocyclohepta-1,3,5-trien-1-yl 3-methylben... 2 1
ethoxy-[6-[ethoxy(oxido)methylidene]-3,7-dioxo-1,5-dihydro-s-i... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00220490 CHEMBL1503330 Bioactive Dipentyl phthalate
CFAMM00220533 DNC002980 Investigative Drug Phthalic Acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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