CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID868
Family Name D-alanyl-D-alanine carboxypeptidase Inhibitor Glycyl-l-alpha-amino-epsilon-pimelyl-d-alanine Family
No. of Seeds 5 No. of Other Members 89
Family Centroid CFAMM00220602 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily D-alanyl-D-alanine carboxypeptidase Inhibitor Glycyl-l-alpha-amino-epsilon-pimelyl-d-alanine Superfamily
Class Class 714

Cousin Family NamesSeedsMembers
Peptidyl-prolyl cis-trans isomerase A and Peptidyl-prolyl cis-... 2 35
Bacterial outer membrane inhibitor polymyxin Colistin Family 26 160
Alpha-2 adrenergic receptor Ligand Guanfacine Extended Release... 5 45
Glutamine receptor Ligand L-alanyl-l-glutamine Family 3 101
Hepatitis C Vaccine family 1 5
Calmodulin Inhibitor N-trimethyllysine Family 1 14
Alanine racemase and Cyclin-dependent kinase 2 Inhibitor Lysin... 1 3
Nitric oxide synthase, inducible Inhibitor (s)-2-amino-6-[(e)-... 2 0
Cathepsin K Inhibitor Boc-agly-val-agly-oet Family 1 20
Farnesyltransferase beta subunit, putative and Protein farnesy... 3 29
Interstitial collagenase Inhibitor Ro-31-4724 Family 2 10
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Alp... 4 18
Cytosolic phospholipase A2 Inhibitor 4-(2-oxohexadecanamido)bu... 1 0
Sodium/glucose cotransporter 1 Inhibitor Qcpac Family 4 7
Cytosolic phospholipase A2 Inhibitor (s)-ethyl 6-(2-oxohexadec... 2 4
Cytosolic phospholipase A2 Inhibitor Ethyl 2-(2-oxohexadecanam... 3 0
Bifunctional epoxide hydrolase 2 Inhibitor 13-(3-n-pentylureid... 2 1
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 6 3
Alpha-galactosidase A Inhibitor AT1001 Family 1 0
Angiotensin-converting enzyme inhibitor SureCN10957020 family 2 1
Endothelin-converting enzyme 1 and Renin inhibitor tert-butyl ... 5 5
Cathepsin L1 and Cathepsin B inhibitor L-Arginine, N2-(N-(N-ac... 1 7
Nucleotide-binding oligomerization domain-containing protein 1... 14 7
Nucleotide-binding oligomerization domain-containing protein 1... 1 0
Proprotein convertase subtilisin/kexin type 6 and Furin inhibi... 3 11
Angiotensin-converting enzyme inhibitor 1-[2-[[carboxy-[1-(car... 2 1
Caspase-1 inhibitor (2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-methy... 1 9
Dihydroxyacetone phosphate acyltransferase inhibitor (2S)-2-(3... 1 2
NAD-dependent protein deacetylase sirtuin-1 and NAD-dependent ... 4 0
Prelamin-A/C and DNA-(apurinic or apyrimidinic site) lyase inh... 1 2
Gastricsin inhibitor 2-[[(2S)-2-[[(2R,5S)-2,7-dimethyl-5-[[(2S... 1 2
Amino Acids and Derivatives Metabolite Pipecolic acid Family 3 5
Amino Acids and Derivatives Metabolite Saccharopine Family 2 1
Amino Acids and Derivatives Metabolite 2-Methylbutyrylglycine ... 2 0
Amino Acids and Derivatives Metabolite Capryloylglycine Family 9 4
Amino Acids and Derivatives Metabolite Hypusine Family 1 0
Amino Acids and Derivatives Metabolite Lysinoalanine Family 1 1
NP (s)-2-(1-((s)-2-amino-3-methylbutanoyl)piperidine-4-carboxa... 10 0
Putative NP ZINC12867126 Family 28 0
2-[(2-azaniumylacetyl)amino]pentanoate NP 2-(2-aminoacetamido)... 3 2
carboxylate NP (r)-tert-butyl 2-(((r)-1-((2-methoxy-2-oxoethyl... 2 3
Putative NP ZINC04027430 Family 6 0
[(2R)-1-[(2-ethoxy-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00220646 CHEMBL1689703 Bioactive 2-amino-6-[[(4R)-4-amino-5-oxo-5-(undecylamino)pentanoyl]amino]heptanedioic acid
CFAMM00220645 CHEMBL1689709 Bioactive AGN-PC-093L4N
CFAMM00220696 CHEMBL1689697 Bioactive 2-amino-6-[[(4R)-4-carboxy-4-(dodecylamino)butanoyl]amino]heptanedioic acid
CFAMM00220686 CHEMBL314442 Bioactive AC1L9JN9
CFAMM00220602 DNC002991 Investigative Drug Glycyl-L-Alpha-Amino-Epsilon-Pimelyl-D-Alanine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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