CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID886
Family Name Herpes simplex virus type 1 thymidine kinase Inhibitor 9-(4-hydroxybutyl)-n2-phenylguanine Family
No. of Seeds 2 No. of Other Members 13
Family Centroid CFAMM00221447 Functional Category Investigative Drug with Natural Product
Superfamily Herpes simplex virus type 1 thymidine kinase and ATP-sensitive inward rectifier potassium channel 10 Binder Superfamily
Class Class 1651

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
Reverse transcriptase Inhibitor Nevirapine Family 23 640
Dipeptidyl peptidase 4 Inhibitor Linagliptin Family 10 81
cAMP-specific 3',5'-cyclic phosphodiesterase 4D Inhibitor Arof... 3 196
Dipeptidyl peptidase 4 Inhibitor SSR-162369 Family 8 27
GP-531 family 1 33
Toll-like receptor 7 Ligand GS-9620 Family 2 4
Adenosine receptor A1 and Adenosine receptor A2a Ligand 8-phen... 12 213
Adenosine receptor A1 and Adenosine receptor A2b Ligand PSB-11... 34 26
Adenosine deaminase Inhibitor FR221647 Family 1 4
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Adenosine receptor A2b Ligand CVT-7124 Family 14 64
Adenosine receptor A2a Ligand (e,e)-8-(4-phenylbutadien-1-yl)c... 11 43
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SCH-577... 9 29
Herpes simplex virus type 1 thymidine kinase Inhibitor N2-(3-t... 1 2
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN1... 6 16
Adenosine receptor A1 ligand SureCN10614388 family 5 1
Adenosine receptor A1 ligand 8-(2-amino-4-nitrophenyl)-1,3-dim... 1 0
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 2 1
Dipeptidyl peptidase 4 inhibitor Xanthine Analogue 4 family 1 4
Dipeptidyl peptidase 4 inhibitor AGN-PC-046QKE family 3 5
Macrophage colony-stimulating factor 1 receptor and Cytochrome... 13 3
Vascular endothelial growth factor receptor 2 ligand AC1LLCDM ... 1 2
Inositol monophosphatase 1 and 15-hydroxyprostaglandin dehydro... 1 0
Prelamin-A/C inhibitor CHEMBL1503535 family 1 0
Cellular tumor antigen p53 and Thyrotropin receptor ligand CHE... 1 5
Adenosine receptor A3 and Adenosine receptor A1 ligand (8R)-8-... 4 0
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 21 32
Adenosine receptor A2a and Adenosine receptor A2b ligand SureC... 2 2
Toll-like receptor 7 ligand 6-amino-2-(butylamino)-9-[[4-(dime... 5 4
Tyrosine-protein kinase ITK/TSK and Receptor-type tyrosine-pro... 1 0
Dipeptidyl peptidase 4 and Potassium voltage-gated channel sub... 4 8
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 10 14
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 0
3-phosphoinositide-dependent protein kinase 1 and RAC-alpha se... 10 4
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 5 4
Platelet-derived growth factor receptor beta and Vascular endo... 5 12
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 4 2
Adenosine receptor A3 ligand 3-(cyclopropylmethyl)-8-methoxy-1... 1 0
Cathepsin K and Cathepsin S inhibitor 2-Cyano-pyrimidine, 17d ... 5 9
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 10 1
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL2... 1 0
Cathepsin K and Cathepsin S inhibitor SureCN4138353 family 3 0
Prothrombin inhibitor 2-[4-methyl-5-[[[2-[6-methyl-2-oxo-3-(2-... 1 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 2
Thromboxane-A synthase inhibitor 6-chloro-3-(4-imidazol-1-ylbu... 12 21
Adenosine receptor A1 ligand 3-(4-Aminophenethyl)-8-(3-noradam... 1 0
Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... 12 7
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 3 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 9 0
Corticotropin-releasing factor receptor 1 ligand AGN-PC-02ZKZ9... 9 12
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00221437 CHEMBL591235 Bioactive 3-[2-(4-aminophenyl)ethyl]-7-[2-[ethyl(2-hydroxyethyl)amino]ethyl]-1-propylpurine-2,6-dione
CFAMM00221447 DNC003028 Investigative Drug 9-(4-Hydroxybutyl)-N2-Phenylguanine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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