CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Methionine aminopeptidase 2 Inhibitor 5-methyl-2-[(phenylsulfonyl)amino]benzoic Acid Family
No. of Seeds 7 No. of Other Members 101
Family Centroid CFAMM00222313 Functional Category Investigative Drug with Natural Product
Superfamily Methionine aminopeptidase 2 Binder Superfamily
Class Class 1854

Cousin Family NamesSeedsMembers
Beta-lactamase Inhibitor 4-[(methylsulfonyl)amino]benzoic Acid... 1 7
Methionine aminopeptidase 2 Inhibitor 2-(phenylsulfonamido)-1-... 3 1
Pol polyprotein inhibitor Cyclooctylpyranonesulfonamide deriv.... 13 1
Aldo-keto reductase family 1 member C3 inhibitor 3-[(3-methyl-... 2 20
Aldo-keto reductase family 1 member C3 and Aldo-keto reductase... 1 2
Bifunctional epoxide hydrolase 2 inhibitor 6-[[1-(2,4-dimethyl... 1 3
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 1
Peroxisome proliferator-activated receptor delta and Peroxisom... 3 18
Methionine aminopeptidase 2 inhibitor AGN-PC-00B6XH family 2 3
Methionine aminopeptidase 2 inhibitor AGN-PC-00DIXW family 3 1
Putative NP ZINC00192342 Family 2 1


External ID

Functional Category

Molecule Name

CFAMM00222248 CHEMBL380394 Bioactive A75
CFAMM00222284 CHEMBL379124 Bioactive sulfonamide compound, 13
CFAMM00222198 DNC006716 Investigative Drug 2-(phenylsulfonamido)-5-propylbenzoic acid
CFAMM00222196 DNC006718 Investigative Drug 3,5-dimethyl-2-(phenylsulfonamido)benzoic acid
CFAMM00222200 DNC006715 Investigative Drug 5-butyl-2-(phenylsulfonamido)benzoic acid
CFAMM00222199 DNC006717 Investigative Drug 5-ethyl-2-(phenylsulfonamido)benzoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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