CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID919
Family Name Peptide deformylase, mitochondrial Inhibitor Furo[2,3d]pyrimidine Antifolate Family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00222340 Functional Category Investigative Drug
Superfamily Peptide deformylase, mitochondrial and Serine/threonine-protein kinase Chk1 Binder Superfamily
Class Class 1877

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase Chk1 Inhibitor N-(5,6-diphenyl... 9 100
Dihydrofolate reductase and Trifunctional purine biosynthetic ... 1 0
Vascular endothelial growth factor receptor 1 and Receptor-typ... 2 11
Activated CDC42 kinase 1 inhibitor 6-(4-methylsulfonylphenyl)-... 2 0
Activated CDC42 kinase 1 inhibitor 6-[4-(2-morpholin-4-ylethox... 7 1
Eukaryotic translation initiation factor 2-alpha kinase 3 inhi... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00222336 CHEMBL596672 Bioactive (2S)-2-[[4-(2,4-diamino-5-methylfuro[2,3-d]pyrimidin-6-yl)sulfanylbenzoyl]amino]pentanedioic acid
CFAMM00222340 DNC003110 Investigative Drug Furo[2,3d]Pyrimidine Antifolate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27526 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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