CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Peptide deformylase, mitochondrial Inhibitor Brodimoprim-4,6-dicarboxylate Family
No. of Seeds 9 No. of Other Members 1
Family Centroid CFAMM00222398 Functional Category Investigative Drug
Superfamily Macitentan Superfamily
Class Class 1208

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Trimethoprim Family 67 482
Hypoxia-inducible factor 1-alpha Inhibitor Hif-1alpha Family 7 107
Insulin-like growth factor 1 receptor Ligand AEW-541 Family 12 140
Peptide deformylase, mitochondrial Inhibitor Epiroprim Family 5 68
Leukotriene B4 receptor 1 ligand AGN-PC-07ZF09 family 3 2
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 1 0
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 5 12
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 21
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 1 3
P2X purinoceptor 3 and P2X purinoceptor 2 inhibitor 2-[[4-amin... 10 9


External ID

Functional Category

Molecule Name

CFAMM00222403 CHEMBL31713 Bioactive AGN-PC-073I8B
CFAMM00222396 CHEMBL46980 Bioactive AGN-PC-073OOT
CFAMM00222404 CHEMBL296525 Bioactive 2-(3-{2-bromo-5-[(2,4-diaminopyrimidin-5-yl)methyl]-3-methoxyphenoxy}propyl)pentanedioic acid
CFAMM00222402 CHEMBL45202 Bioactive AC1L9ZWY
CFAMM00222395 CHEMBL31887 Bioactive AGN-PC-073I8U
CFAMM00222400 CHEMBL31924 Bioactive AGN-PC-073I2N
CFAMM00222399 CHEMBL286400 Bioactive 6-[2-bromo-5-[(2,4-diaminopyrimidin-5-yl)methyl]-3-methoxyphenoxy]hexanoic acid
CFAMM00222397 CHEMBL44684 Bioactive AGN-PC-037VAE
CFAMM00222398 DNC003118 Investigative Drug Brodimoprim-4,6-Dicarboxylate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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