CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID926
Family Name Cathepsin S Inhibitor 2-[(2',3',4'-trifluorobiphenyl-2-yl)oxy]ethanol Family
No. of Seeds 2 No. of Other Members 16
Family Centroid CFAMM00222422 Functional Category Investigative Drug
Superfamily Cathepsin S Inhibitor 2-[(2',3',4'-trifluorobiphenyl-2-yl)oxy]ethanol Superfamily
Class Class 614

Cousin Family NamesSeedsMembers
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Muscarinic acetylcholine receptor M1 Ligand GSK1034702 Family 7 148
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Cytosolic phospholipase A2 Inhibitor 1,1,1-trifluoro-6-(4-hexy... 9 86
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 214
NAD(P)H dehydrogenase [quinone] 1 Inhibitor NSC-106547 Family 3 65
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 4 37
Amine oxidase [flavin-containing] B Inhibitor 7-fluoro-2-p-tol... 4 11
Prostaglandin G/H synthase 1 Inhibitor 2-(2-methoxyphenyl)-1h-... 1 11
Phenols and Derivatives Metabolite (±)-Flufenprox Family 1 13


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00222433 CHEMBL390945 Bioactive Aldehyde Inhibitor, 12e
CFAMM00222422 DNC003125 Investigative Drug 2-[(2',3',4'-TRIFLUOROBIPHENYL-2-YL)OXY]ETHANOL

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27425 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543