CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Leukotriene A-4 hydrolase Inhibitor 4-(2-amino-1,3-thiazol-4-yl)phenol Family
No. of Seeds 3 No. of Other Members 13
Family Centroid CFAMM00222605 Functional Category Investigative Drug with Natural Product
Superfamily Leukotriene A-4 hydrolase Inhibitor 4-(2-amino-1,3-thiazol-4-yl)phenol Superfamily
Class Class 1887

Cousin Family NamesSeedsMembers
Adenosine receptor A1 and Adenosine receptor A2a Ligand LUF-54... 2 19
Collagenase 3 Inhibitor 4-(methyl(4-phenylthiazol-2-yl)amino)p... 2 0
Polyphenol oxidase 2 and Niemann-Pick C1 protein inhibitor NSC... 1 3
Survival motor neuron protein and Microtubule-associated prote... 1 20
Adenosine receptor A1 ligand 7-methoxy-4,5-dihydrobenzo[e][1,3... 2 2
Transitional endoplasmic reticulum ATPase and Beta-lactamase i... 1 1
Huntingtin and Ras-related protein Rab-9A inhibitor CHEMBL1400... 1 3
Urokinase-type plasminogen activator inhibitor AGN-PC-01XMBP f... 3 7
DNA-(apurinic or apyrimidinic site) lyase and DNA polymerase b... 1 0
Kynurenine 3-monooxygenase inhibitor N-[4-(4-hydroxy-3-methylp... 1 0


External ID

Functional Category

Molecule Name

CFAMM00222605 DNC003144 Investigative Drug 4-(2-amino-1,3-thiazol-4-yl)phenol
CFAMM00222610 DNC014079 Investigative Drug 2-(4-(4-Hydroxyphenyl)thiazol-2-ylamino)phenol
CFAMM00222609 DNC014078 Investigative Drug 3-(4-(4-Hydroxyphenyl)thiazol-2-ylamino)phenol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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