CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID948
Family Name Cathepsin L1 Inhibitor Biphenyl-4-yl-acetaldehyde Family
No. of Seeds 2 No. of Other Members 86
Family Centroid CFAMM00222859 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily Cathepsin L1 Inhibitor Biphenyl-4-yl-acetaldehyde Superfamily
Class Class 1897

Cousin Family NamesSeedsMembers
Aldehyde oxidase inhibitor para-naphthoquinone Menadione Family 22 503
Cyclooxygenase Inhibitor Flurbiprofen Family 18 294
Prostaglandin G/H synthase 2 Inhibitor Ketoprofen Family 5 84
Vitamin K epoxide reductase complex subunit 1 Inhibitor Phenin... 5 44
Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Diet... 29 276
DNA topoisomerase 2-beta Inhibitor Salvicine Family 2 9
Carboxypeptidase B2 Inhibitor Dl-benzylsuccinic Acid Family 1 11
Cytosolic phospholipase A2 Inhibitor 1,1,1,2,2-pentafluoro-8-p... 11 18
Liver carboxylesterase 1 Inhibitor 1,2-bis(2,3,6-trifluorophen... 16 11
Liver carboxylesterase 1 Inhibitor 1-(4-chloro-phenyl)-2-pheny... 5 47
72 kDa type IV collagenase and Macrophage metalloelastase Inhi... 2 5
Thyroid hormone receptor alpha and Thyroid hormone receptor be... 2 8
Liver carboxylesterase 1 Inhibitor Acenanthrene-9,10-dione Family 2 12
Cytosolic phospholipase A2 Inhibitor 1,1,1-trifluoro-6-(naphth... 1 3
4-hydroxyphenylpyruvate dioxygenase Inhibitor 2-(2-iodo-benzoy... 3 1
Neuraminidase Inhibitor (e,e)-1,7-diphenyl-4,6-heptadien-3-one... 2 5
Aromatase inhibitor (6R)-6-benzyl-10,13-dimethyl-2,6,7,8,9,11,... 1 29
Shiga toxin 1 variant B subunit and Shiga toxin 1 variant A su... 1 13
Chymotrypsinogen B inhibitor (6E)-6-(iodomethylidene)-4-phenyl... 1 1
Cocaine esterase and Liver carboxylesterase 1 inhibitor 1-brom... 1 1
Sodium-dependent dopamine transporter inhibitor AGN-PC-074TA8 ... 2 5
Neprilysin and Angiotensin-converting enzyme inhibitor 5-benzy... 1 2
Carboxylic Acids and Derivatives Metabolite 3-Acetoxy-3-methyl... 2 0
Prenol Lipids Metabolite 11,12-Dihydrolactaroviolin Family 2 2
Indanes Metabolite Pterosin F Family 1 1
Prenol Lipids Metabolite Myrigalone A Family 1 1
NP 4-methoxydalbergione Family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00222829 DNC005396 Investigative Drug (R)-3-(4-Isobutyl-phenyl)-butan-2-one
CFAMM00222859 DNC003188 Investigative Drug BIPHENYL-4-YL-ACETALDEHYDE

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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