CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Peroxisome proliferator-activated receptor gamma and Retinoic acid receptor RXR-alpha Ligand 2-chloro-5-nitro-n-phenylbenzamide Family
No. of Seeds 4 No. of Other Members 9
Family Centroid CFAMM00224033 Functional Category Investigative Drug
Superfamily Retinoic acid receptor RXR-alpha and MO15-related protein kinase Pfmrk Binder Superfamily
Class Class 1913

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Meclofenamic Acid Family 4 11
Pan-DAC Inhibitor AR-42 Family 21 153
Phospholipase D1 Inhibitor Halopemide Family 17 111
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(2,4... 3 6
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(... 2 17
Metabotropic glutamate receptor 5 Ligand N-(3-acetamidophenyl)... 4 20
MO15-related protein kinase Pfmrk Inhibitor 2-chloro-n-(o-toly... 6 28
Metabotropic glutamate receptor 5 Ligand 3-cyano-n-(3-cyanophe... 7 5
D(3) dopamine receptor and Alpha-1B adrenergic receptor ligand... 11 8
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 3
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 4 6
Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3... 1 5
Poly [ADP-ribose] polymerase 2 and Poly [ADP-ribose] polymeras... 1 0
G protein-activated inward rectifier potassium channel 4 and G... 1 0


External ID

Functional Category

Molecule Name

CFAMM00224039 DNC014783 Investigative Drug N-(3,5-dichlorophenyl)-2-methyl-3-nitrobenzamide
CFAMM00224017 DNC009898 Investigative Drug 4-chloro-N-(2,5-dichlorophenyl)-3-nitrobenzamide
CFAMM00224033 DNC003265 Investigative Drug 2-chloro-5-nitro-N-phenylbenzamide
CFAMM00224014 DNC009897 Investigative Drug N-(2,4-dichlorophenyl)-4-methyl-3-nitrobenzamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



67803 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543