CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID989
Family Name Penicillin-binding protein 1B Inhibitor N-benzoyl-d-alanine Family
No. of Seeds 1 No. of Other Members 40
Family Centroid CFAMM00224425 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily Penicillin-binding protein 1B Inhibitor N-benzoyl-d-alanine Superfamily
Class Class 1315

Cousin Family NamesSeedsMembers
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
Amine oxidase [flavin-containing] A Inhibitor Moclobemide Family 5 255
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 16 374
Tyrosine 3-monooxygenase Inhibitor L-phenylalanine Family 19 144
Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Diet... 29 276
Angiotensin-converting enzyme Inhibitor Spirapril Family 17 86
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 7 54
ATP-sensitive inward rectifier potassium channel 10 Ligand Nat... 3 233
DNA Binder Procarbazine Family 8 358
Bacterial outer membrane Inhibitor Polymyxin B Family 17 181
Angiotensin-converting enzyme and Neprilysin Inhibitor M100,24... 18 60
Iofolastat I-124 family 6 33
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
Hemagglutinin Inhibitor Cl 385319 Family 18 101
Neutrophil elastase Inhibitor FK-706 Family 8 85
Neprilysin Inhibitor Thiorphan Family 41 68
Cathepsin F and Cruzipain Inhibitor WRR-99 Family 13 131
Thymidylate synthase Inhibitor Sp-876 Family 7 117
Carbonic anhydrase 2 Inhibitor N-benzyl-4-sulfamoyl-benzamide ... 12 44
Integrin alpha-V and Integrin beta-3 Inhibitor Cyclo-[-arg-gly... 5 38
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Farnesyltransferase beta subunit, putative and Protein farnesy... 24 82
Plasmepsin-2 Inhibitor PS-222036 Family 12 134
Integrin beta-3 Inhibitor L-709780 Family 9 10
Integrin beta-3 Inhibitor DMP-728 Family 3 0
Histone deacetylase 1 Inhibitor 8-(3-benzoyl-ureido)-octanoic ... 7 13
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(6... 1 12
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Trifunctional purine biosynthetic protein adenosine-3 Inhibito... 2 11
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 6 24
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 3 21
Histone deacetylase 1 and Histone deacetylase 4 Inhibitor Azum... 3 10
Cannabinoid receptor 1 Ligand N-(3,3-diphenyl)propyl-2-phenyla... 4 18
Cytosolic phospholipase A2 Inhibitor Methyl 2-(2-oxo-8-phenylo... 2 3
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 6 19
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-137546 Family 1 3
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-348926 Family 2 15
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Inhibit... 5 23
Cathepsin S Inhibitor N-(1-oxobutan-2-yl)-3-(trifluoromethyl)b... 2 10
Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-n-methyl-benza... 3 9
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Aminopeptidase N Inhibitor 2-cinnamamido-n4-hexyl-n1-hydroxysu... 24 8
Cholecystokinin receptor type A Ligand CR-1795 Family 19 41
Angiotensin-converting enzyme inhibitor (S)-1-((S)-5-benzamido... 5 2
Chymotrypsin-like elastase family member 2A and Chymotrypsinog... 2 18
72 kDa type IV collagenase and Matrilysin inhibitor (2S,3R)-N-... 1 0
Angiotensin-converting enzyme inhibitor AGN-PC-00LXSR family 7 1
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7285564... 1 2
Neprilysin inhibitor SureCN489232 family 3 9
Mitogen-activated protein kinase 14 and Cytochrome P450 2C9 in... 2 0
Dipeptidyl peptidase 4 inhibitor 4-cyano-N-[4-[(2S)-2-cyanopyr... 1 1
Integrin beta-3 and Integrin alpha-IIb inhibitor AGN-PC-074AY6... 1 0
Chymase and Chymotrypsinogen B inhibitor AGN-PC-075LTI family 2 3
Angiotensin-converting enzyme and Angiotensin-converting enzym... 1 0
Angiotensin-converting enzyme inhibitor SureCN7263641 family 2 11
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 0
Cystathionine beta-lyase MetC inhibitor N-(2-hydrazinyl-2-oxoe... 1 0
Genome polyprotein inhibitor Benzoyl-KKR-H family 1 1
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor AGN-PC... 2 9
Integrin beta-1 and Integrin alpha-4 inhibitor (3S,6R,11R,14S)... 2 0
Caspase-1 inhibitor (3S)-4-oxo-3-[[(2S)-4-oxo-4-[(3-oxo-3-phen... 1 1
Nonstructural protein 1 inhibitor CHEMBL1582638 family 1 0
Integrin beta-1 and Integrin alpha-4 inhibitor 6-[4-[(2S)-2-ca... 1 0
Transcriptional activator protein LasR and Transcriptional act... 3 2
PhzR inhibitor tert-butyl N-[[4-[[(3S)-2-oxooxolan-3-yl]carbam... 1 0
Tubulin beta-1 chain inhibitor SureCN6672529 family 1 0
4-methyl-2-[[(E)-3-phenylprop-2-enyl]azaniumyl]pentanoate NP 2... 4 6
NP Methyl 5-((2s,3s,4r)-4-benzamido-3-chlorotetrahydrothiophen... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00224425 DNC003280 Investigative Drug N-BENZOYL-D-ALANINE

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48716 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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