CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP1062
Family Name 3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxole NP (3ar,5r,6s,6ar)-5-((r)-2,2-dimethyl-1,3-dioxolan-4-yl)-6-((4-isopropoxybenzyl)oxy)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole Family
No. of Seeds 18 No. of Other Members 6
Family Centroid CFAMM00557014 Functional Category Natural Product
Superfamily Huntingtin and Nonstructural protein 1 Binder Superfamily 4
Class Class 944

Cousin Family NamesSeedsMembers
Salicin family 5 629
Sodium/glucose cotransporter 2 Inhibitor Empagliflozin Family 32 52
Glucokinase Inhibitor R7201 Family 22 105
TS-071 family 8 36
Cytochrome P450 3A4 Inhibitor (8r,8'r,9's)-5-methoxyclusin Family 6 20
Tyrosine-protein phosphatase non-receptor type 1 and Neuramini... 10 2
Amine oxidase [flavin-containing] B Inhibitor Methyl Piperate ... 1 19
Prelamin-A/C and Solute carrier organic anion transporter fami... 1 15
Beta-lactamase inhibitor AGN-PC-0A9UJZ family 1 3
Acetylcholinesterase inhibitor (2R,3S,4S,5R,6S)-2-(hydroxymeth... 1 1
Sugar Acids and Derivatives Metabolite 3-Methoxy-4-hydroxyphen... 1 6
Glycosyl Compounds Metabolite Taxiphyllin Family 2 9
Benzyloxycarbonyls Metabolite 4-Methoxybenzyl formate Family 1 7
Acetals Metabolite 1-Benzyloxy-1-(2-methoxyethoxy)ethane Family 3 50
Phenols and Derivatives Metabolite 2-Ethoxy-4-(4-methyl-1,3-di... 1 0
2-(4-methoxyphenyl)-10,10-dimethyl-1,3,9-trioxaspiro[5.5]undec... 4 19


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00557019 ZINC12660552 Natural Product (3aR,5R,6S,6aR)-5-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]-6-[(4-methoxyphenyl)methoxy]-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxole
CFAMM00557006 ZINC12660625 Natural Product (3aR,5R,6S,6aR)-5-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethyl-6-[(4-propan-2-yloxyphenyl)methoxy]-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxole
CFAMM00556997 ZINC05727164 Natural Product (3aR,5R,6S,6aR)-5-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethyl-6-[[4-(2-methylpropoxy)phenyl]methoxy]-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxole
CFAMM00557005 ZINC05951580 Natural Product (3aR,5R,6S,6aR)-6-[(4-butoxyphenyl)methoxy]-5-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxole
CFAMM00557018 ZINC04029313 Natural Product (3aR,5R,6S,6aR)-5-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-6-((4-isobutoxybenzyl)oxy)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole
CFAMM00557004 ZINC08833988 Natural Product (3a'R,5'R,6'S,6a'R)-6'-((4-methoxybenzyl)oxy)-5'-((R)-1,4-dioxaspiro[4.5]decan-2-yl)tetrahydrospiro[cyclohexane-1,2'-furo[2,3-d][1,3]dioxole]
CFAMM00557017 ZINC12660479 Natural Product (3aR,5R,6S,6aR)-5-[(3S)-1,4-dioxaspiro[4.5]decan-3-yl]-6-[[4-(2-methylpropoxy)phenyl]methoxy]spiro[3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxole-2,1'-cyclohexane]
CFAMM00557010 ZINC05953602 Natural Product (3aR,5R,6S,6aR)-5-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]-6-[(4-ethoxyphenyl)methoxy]-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxole
CFAMM00557016 ZINC04029364 Natural Product (3aR,5R,6S,6aR)-5-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-6-((4-methoxybenzyl)oxy)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole
CFAMM00557009 ZINC04029485 Natural Product (3aR,5R,6S,6aR)-5-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-6-((4-isopropoxybenzyl)oxy)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole
CFAMM00557000 ZINC12660582 Natural Product (3aR,5R,6S,6aR)-5-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethyl-6-[(4-propoxyphenyl)methoxy]-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxole
CFAMM00557015 ZINC12660596 Natural Product (3aR,5R,6S,6aR)-5-[(3S)-1,4-dioxaspiro[4.5]decan-3-yl]-6-[(4-methoxyphenyl)methoxy]spiro[3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxole-2,1'-cyclohexane]
CFAMM00557008 ZINC12660480 Natural Product (3a'R,5'R,6'S,6a'R)-6'-((4-isobutoxybenzyl)oxy)-5'-((R)-1,4-dioxaspiro[4.5]decan-2-yl)tetrahydrospiro[cyclohexane-1,2'-furo[2,3-d][1,3]dioxole]
CFAMM00556999 ZINC08833986 Natural Product (3aR,5R,6S,6aR)-5-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyl-6-((4-(pentyloxy)benzyl)oxy)tetrahydrofuro[2,3-d][1,3]dioxole
CFAMM00557014 ZINC04029421 Natural Product (3aR,5R,6S,6aR)-5-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyl-6-((4-propoxybenzyl)oxy)tetrahydrofuro[2,3-d][1,3]dioxole
CFAMM00557007 ZINC12660701 Natural Product (3aR,5R,6S,6aR)-5-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethyl-6-[(4-pentoxyphenyl)methoxy]-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxole
CFAMM00557020 ZINC04029418 Natural Product (3aR,5R,6S,6aR)-5-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-6-((4-ethoxybenzyl)oxy)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole
CFAMM00556998 ZINC04029513 Natural Product (3aR,5R,6S,6aR)-6-((4-butoxybenzyl)oxy)-5-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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