CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP1190
Family Name Putative NP ZINC08790868 Family
No. of Seeds 10 No. of Other Members 0
Family Centroid CFAMM00558268 Functional Category Natural Product
Superfamily Ras-related protein Rab-9A and Niemann-Pick C1 protein inhibitor CHEMBL1414703 Superfamily
Class Class 288

Cousin Family NamesSeedsMembers
Alpha-1 adrenergic receptor ligand arylethanolamine derivative... 4 37
C-C chemokine receptor type 5 Ligand GW873140 Family 6 78
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Leukotriene B4 receptor 1 Ligand SC-51146 Family 6 315
Acetylcholinesterase and Cholinesterase Inhibitor 3-[7-(benzyl... 22 303
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Beta-2 adrenergic receptor Ligand Gnf-pf-1694 Family 4 70
C-C chemokine receptor type 1 and Chemokine (C-C motif) recept... 1 16
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 2 110
Cathepsin D inhibitor (E)-N-butyl-4-[1-(3,4,5-trimethoxybenzoy... 1 3
Calpain-1 catalytic subunit inhibitor (3S)-3-[[4-[2-(methoxyme... 2 4
Putative NP ZINC08790414 Family 23 0
NP 2-(5,7-dihydroxy-4-methyl-2-oxo-2h-chromen-3-yl)-n-(3-(fura... 6 0
NP (z)-2-(4-isopropylbenzylidene)-3-oxo-2,3-dihydrobenzofuran-... 16 0
Putative NP ZINC02124510 Family 1 0
NP 2-((5-hydroxy-2,2-dimethyl-4-oxochroman-7-yl)oxy)-n-(3-meth... 18 0
Putative NP ZINC04085259 Family 3 0
NP 1-(2-((1-hydroxy-7-methoxy-9-oxo-9h-xanthen-3-yl)oxy)acetyl... 2 0
NP 2-((1'-acetyl-4-oxospiro[chroman-2,4'-piperidin]-7-yl)oxy)-... 5 0
NP 5-hydroxy-4-oxo-2-phenyl-4h-chromen-7-yl 2-((tert-butoxycar... 19 0
NP 7-(2-((4as,8as)-4a-hydroxyoctahydroisoquinolin-2(1h)-yl)-2-... 3 0
hydroxyspiro[3H-chromene-2,4'-piperidine]-4-one NP 1'-acetyl-7... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00558267 ZINC08879708 Natural Product N-[[(2R)-1-ethylpyrrolidin-1-ium-2-yl]methyl]-2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetamide
CFAMM00558260 ZINC12296886 Natural Product AGN-PC-067F0Z
CFAMM00558266 ZINC09059034 Natural Product (2S)-2-[[2-[[(2Z)-2-[(2,4-dimethoxyphenyl)methylidene]-3-oxo-1-benzofuran-6-yl]oxy]acetyl]amino]-3-hydroxypropanoate
CFAMM00558259 ZINC08880090 Natural Product (R)-N-(1-hydroxy-3-phenylpropan-2-yl)-2-((5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy)acetamide
CFAMM00558265 ZINC04085608 Natural Product (2S)-3-hydroxy-2-[[2-[[(2Z)-2-[(4-methoxyphenyl)methylidene]-3-oxo-1-benzofuran-6-yl]oxy]acetyl]amino]propanoate
CFAMM00558264 ZINC08765361 Natural Product (S)-N-(1-hydroxy-4-(methylthio)butan-2-yl)-2-((5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy)acetamide
CFAMM00558263 ZINC08879713 Natural Product N-[[(2S)-1-ethylpyrrolidin-1-ium-2-yl]methyl]-2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetamide
CFAMM00558262 ZINC12886122 Natural Product (2R)-3-(4-hydroxyphenyl)-2-[[2-[[(2Z)-2-[(4-methoxyphenyl)methylidene]-3-oxo-1-benzofuran-6-yl]oxy]acetyl]amino]propanoate
CFAMM00558268 ZINC08790868 Natural Product (2S)-3-(4-hydroxyphenyl)-2-[[2-[[(2Z)-2-[(4-methoxyphenyl)methylidene]-3-oxo-1-benzofuran-6-yl]oxy]acetyl]amino]propanoate
CFAMM00558261 ZINC08917795 Natural Product (2R)-2-[[2-[3-hydroxy-4-(2-phenoxyacetyl)phenoxy]acetyl]amino]-4-methylsulfanylbutanoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

42885 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543