CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP1229
Family Name 5,6-dihydro-4H-furo[2',3':3,4]cyclohepta[1,2-b][1]benzofuran NP (7r)-4,7,15-trimethyl-7-phenyl-3,11-dioxatetracyclo[^{2,6}.0^{12,17}]heptadeca-1(10),2(6),4,12(17),13,15-hexaene Family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00558539 Functional Category Natural Product
Superfamily 5,6-dihydro-4H-furo[2',3':3,4]cyclohepta[1,2-b][1]benzofuran NP (7r)-4,7,15-trimethyl-7-phenyl-3,11-dioxatetracyclo[^{2,6}.0^{12,17}]heptadeca-1(10),2(6),4,12(17),13,15-hexaene and 2,4-dimethyl-5,6-dihydro-4H-furo[2',3':3,4]cyclohepta[1,2-b][1]benzofuran NP ZINC02057927 Superfamily
Class Class 628

Cousin Family NamesSeedsMembers
Potassium voltage-gated channel subfamily H member 2 Ligand Am... 2 16
DNA Binder Methoxsalen Family 10 1638
Ipriflavone family 62 2480
Agrimophol family 10 22
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Multidrug resistance-associated protein 1 Inhibitor Benzbromar... 2 16
Estrogen receptor beta Ligand 2-(4-hydroxy-phenyl)benzofuran-5... 5 82
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor (2,5... 1 9
Oestrogen receptor and Estrogen receptor beta Ligand 7-chloro-... 2 27
Phospholipase A2 Inhibitor 3,9-dihydroxy-2,10-diprenylpterocap... 9 25
Platelet-derived growth factor receptor beta Ligand Bis(5-meth... 5 220
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Protein kinase C gamma type and Protein kinase C alpha type In... 2 1
Fatty-acid amide hydrolase 1 Inhibitor Benzofuran-2-ylboronic ... 1 14
Retinoic acid receptor RXR-alpha and Peroxisome proliferator-a... 3 17
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 1 1
Cytochrome P450 3A4 inhibitor 4-[(2E)-6-[(E)-3-hydroxy-2,6-dim... 3 2
Furans Metabolite 2,4-Difurfurylfuran Family 1 0
Prenol Lipids Metabolite Ipomeamaronol Family 2 2
Naphthofurans Metabolite Pyrocurzerenone Family 1 9
NP 6-(4-ethoxyphenyl)-1,3-dimethyl-4-oxo-4h-cyclohepta[c]furan... 13 3
1,3-dimethylcyclohepta[c]furan-8-one NP 8-hydroxy-6-(4-methoxy... 10 0
NP 2,2,11,12-tetramethyl-3,4,8,9-tetrahydro-2h-cyclopenta[c]fu... 3 1
Putative NP ZINC05219435 Family 4 0


External ID

Functional Category

Molecule Name

CFAMM00558540 ZINC02911795 Natural Product (7R)-7-(4-methoxyphenyl)-4,7,15-trimethyl-3,11-dioxatetracyclo[^{2,6}.0^{12,17}]heptadeca-1(10),2(6),4,12(17),13,15-hexaene
CFAMM00558539 ZINC02494749 Natural Product (7R)-4,7,15-trimethyl-7-phenyl-3,11-dioxatetracyclo[^{2,6}.0^{12,17}]heptadeca-1(10),2(6),4,12(17),13,15-hexaene
CFAMM00558538 ZINC12660006 Natural Product AGN-PC-052AUU

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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