CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Putative NP ZINC49600254 Family
No. of Seeds 8 No. of Other Members 2
Family Centroid CFAMM00549636 Functional Category Natural Product
Superfamily Glutamate carboxypeptidase 2 inhibitor 2-[(3-hydroxyphenyl)methyl]-3-phosphonopropanoic acid Superfamily
Class Class 2550

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Diflunisal Family 7 421
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Prostaglandin G/H synthase 1 Inhibitor Salicyclic Acid Family 3 39
Cyclooxygenase inhibitor salicylate derivative Aspirin family 3 234
Estrogen receptor beta Ligand Conjugated Estrogens Family 12 210
Danthron family 11 141
Mitogen-activated protein kinase 12 Inhibitor SCIO-469 Family 1 7
Macrophage migration inhibitory factor and Prothrombin Inhibit... 2 49
Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 I... 2 19
Steryl-sulfatase Inhibitor 3-{4-[(aminosulfonyl)oxy]benzoyl}ph... 5 3
Steryl-sulfatase Inhibitor Sulfamic Acid 3-(4-hydroxy-benzoyl)... 3 2
Epidermal growth factor receptor Ligand AG-538 Family 5 11
Estrogen receptor beta Ligand 3,6-dihydroxy-2-(4-hydroxy-pheny... 2 23
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
4-aminobutyrate aminotransferase, mitochondrial and Succinate-... 4 22
Tyrosine-protein phosphatase non-receptor type 1 Ligand Licoag... 9 32
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-(6-hydroxy-2-nap... 7 9
Arachidonate 12-lipoxygenase, 12S-type and Arachidonate 15-lip... 3 7
Indoleamine 2,3-dioxygenase 1 Inhibitor Garveatin E Family 2 0
Protein farnesyltransferase subunit beta Inhibitor Cylindrol A... 3 43
Tyrosinase Inhibitor 3-(2,4-dihydroxyphenyl)-propionic Acid Et... 3 8
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 14
Thromboxane A2 receptor ligand AGN-PC-003UTI family 1 0
Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 i... 1 0
Peroxisome proliferator-activated receptor gamma and Peroxisom... 1 2
Benzyl Alcohols and Derivatives Metabolite (2R,3S)-Piscidic ac... 1 1
Benzofurans Metabolite 4-Hydroxyphthalide Family 1 1
Benzoic Acid and Derivatives Metabolite Methyl 3-(2,3-dihydrox... 1 3
Putative NP ZINC31158464 Family 3 5
Putative NP ZINC03197541 Family 1 0


External ID

Functional Category

Molecule Name

CFAMM00549643 ZINC31159068 Natural Product 5-carboxy-2-[(2S,6S)-2,7-dihydroxy-6-methylheptan-2-yl]phenolate
CFAMM00549642 ZINC49600257 Natural Product 5-carboxy-2-[(2S,6S)-2,6,7-trihydroxy-6-methylheptan-2-yl]phenolate
CFAMM00549647 ZINC49600258 Natural Product 5-carboxy-2-[(2R,6R)-2,6,7-trihydroxy-6-methylheptan-2-yl]phenolate
CFAMM00549639 ZINC49600260 Natural Product 5-carboxy-2-[(2R,6S)-2,6,7-trihydroxy-6-methylheptan-2-yl]phenolate
CFAMM00549646 ZINC49600254 Natural Product 5-carboxy-2-[(2S,6R)-2,6,7-trihydroxy-6-methylheptan-2-yl]phenolate
CFAMM00549638 ZINC31159056 Natural Product 5-carboxy-2-[(2R,6R)-2,7-dihydroxy-6-methylheptan-2-yl]phenolate
CFAMM00549645 ZINC31159060 Natural Product 5-carboxy-2-[(2R,6S)-2,7-dihydroxy-6-methylheptan-2-yl]phenolate
CFAMM00549644 ZINC31159064 Natural Product 5-carboxy-2-[(2S,6R)-2,7-dihydroxy-6-methylheptan-2-yl]phenolate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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