CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP1302
Family Name 7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinoline NP ZINC33345333 Family
No. of Seeds 21 No. of Other Members 3
Family Centroid CFAMM00559128 Functional Category Natural Product
Superfamily 5-hydroxytryptamine receptor 2A Binder Superfamily
Class Class 38

Cousin Family NamesSeedsMembers
Voltage-dependent T-type calcium channel subunit alpha-1I liga... 5 209
D(1B) dopamine receptor Ligand Apomorphine Family 30 271
Neuronal acetylcholine receptor subunit alpha-2 Ligand Metocur... 18 169
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
5-hydroxytryptamine receptor 2A Ligand Phenethylamine Family 3 25
Tubulin beta chain Inhibitor Colchinol Family 3 109
D(2) dopamine receptor and Sodium-dependent dopamine transport... 6 10
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 11
Dipeptidyl peptidase 4 inhibitor SureCN664019 family 4 5
Benzazepines Metabolite N-Methylporphyroxine Family 1 2
Putative NP ZINC12858318 Family 42 0
Putative NP ZINC12660125 Family 8 0
Putative NP ZINC04287792 Family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00559125 ZINC20760455 Natural Product (5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinoline-5-carbonitrile
CFAMM00559138 ZINC33345333 Natural Product AC1LUOMY
CFAMM00559131 ZINC20113298 Natural Product 3-[(5S)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]prop-2-ynyl-dimethylazanium
CFAMM00559124 ZINC20111895 Natural Product AC1LXF49
CFAMM00559130 ZINC20311224 Natural Product 4-methoxy-6-methyl-5-(nitromethyl)-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline
CFAMM00559143 ZINC20113879 Natural Product AC1OEK42
CFAMM00559123 ZINC20760459 Natural Product 4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline-5-carbonitrile
CFAMM00559136 ZINC19362271 Natural Product [(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]methylazanium
CFAMM00559129 ZINC20111897 Natural Product 3-(4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)prop-2-yn-1-ol
CFAMM00559142 ZINC20113871 Natural Product 4-methoxy-6-methyl-5-(1-nitropropyl)-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline
CFAMM00559122 ZINC33318753 Natural Product 4-methoxy-6-methyl-5-(1-nitroethyl)-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline
CFAMM00559128 ZINC20311221 Natural Product AC1LINYV
CFAMM00559141 ZINC20113301 Natural Product 3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]prop-2-ynyl-dimethylazanium
CFAMM00559134 ZINC00402960 Natural Product 4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium
CFAMM00559127 ZINC20113215 Natural Product (5R)-4-methoxy-6-methyl-5-(3-pyrrolidin-1-ium-1-ylprop-1-ynyl)-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinoline
CFAMM00559140 ZINC20113874 Natural Product AC1LILA8
CFAMM00559133 ZINC20410810 Natural Product AC1OELR6
CFAMM00559126 ZINC20113213 Natural Product (5S)-4-methoxy-6-methyl-5-(3-pyrrolidin-1-ium-1-ylprop-1-ynyl)-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinoline
CFAMM00559139 ZINC20113877 Natural Product AC1O741M
CFAMM00559145 ZINC19370290 Natural Product [(5S)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]methylazanium
CFAMM00559132 ZINC20410813 Natural Product AC1OELR0

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27746 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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