CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP1337
Family Name Putative NP ZINC04061066 Family
No. of Seeds 18 No. of Other Members 0
Family Centroid CFAMM00559388 Functional Category Natural Product
Superfamily Aldose reductase inhibitor AGN-PC-0AKSR2 Superfamily
Class Class 3282

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 61 433
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Alpha adrenergic receptor Ligand Phenoxybenzamine Family 4 63
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Oestrogen receptor Ligand Lasofoxifene Family 19 152
Zucapsacin family 7 177
Serine/threonine-protein kinase PLK1 Inhibitor On 019190.na Fa... 16 138
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 6 33
D(3) dopamine receptor Ligand U-99194A Family 7 33
Dapoxetine family 3 40
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Guanylate cyclase soluble subunit beta-1 Inhibitor Cinaciguat ... 7 50
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83
Histamine H3 receptor Ligand A-331440 Family 6 7
Histamine H3 receptor Ligand UCL-2138 Family 23 172
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Histamine H3 receptor Ligand A-349821 Family 49 228
Adenosine receptor A3 and Muscarinic acetylcholine receptor M2... 4 31
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 41
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 11
Sodium-dependent serotonin transporter Inhibitor 4-(2-((dimeth... 3 1
Sodium-dependent noradrenaline transporter Inhibitor WAY-25680... 4 6
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 13
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 10 15
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 2 3
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
Peroxisome proliferator-activated receptor delta and Peroxisom... 20 8
Substance-P receptor ligand AGN-PC-02K8FR family 1 3
5-hydroxytryptamine receptor 2A and Potassium voltage-gated ch... 2 8
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 11 2
Histamine H3 receptor and Sodium-dependent serotonin transport... 15 1
Orexin receptor type 1 and Orexin receptor type 2 ligand [(2S)... 3 1
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 28
Histamine H3 receptor ligand 1-[[4-[4-[(1R)-4-(4-methoxyphenox... 2 1
Prostaglandin D2 receptor 2 and Chemoattractant receptor-homol... 1 1
Histamine H3 receptor and Sodium-dependent serotonin transport... 6 1
Sodium-dependent serotonin transporter and Histamine H3 recept... 7 0
Sodium-dependent serotonin transporter and Histamine H3 recept... 7 0
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 2
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 6
Lanosterol synthase and Cycloartenol synthase inhibitor 2-hydr... 1 1
Histamine H3 receptor and Histamine H1 receptor ligand AGN-PC-... 1 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 0
Metabotropic glutamate receptor 2 ligand (5R)-3-[[4-(4-ethoxyp... 3 9
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 2 3
Putative NP ZINC38201335 Family 8 0
NP N-(4-chlorobenzyl)-n-(3-(4-isopropoxyphenyl)-3-phenylpropyl... 6 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00559391 ZINC00856787 Natural Product N-(2-(4-benzyl-2,2-dimethyltetrahydro-2H-pyran-4-yl)ethyl)-N-(4-methoxybenzyl)propionamide
CFAMM00559397 ZINC04073440 Natural Product AC1OF2HH
CFAMM00559390 ZINC00856786 Natural Product AC1LM0CK
CFAMM00559396 ZINC12660778 Natural Product N-[(4-methoxyphenyl)methyl]-N-[(3R)-3-(2-methoxyphenyl)-3-(4-propan-2-yloxyphenyl)propyl]propanamide
CFAMM00559389 ZINC09033141 Natural Product N-(4-isopropoxybenzyl)-N-(3-(2-methoxyphenyl)-3-(4-methoxyphenyl)propyl)propionamide
CFAMM00559402 ZINC04043175 Natural Product N-[(4-methoxyphenyl)methyl]-N-[2-[(2S,4S)-4-(4-methylphenyl)-2-propan-2-yloxan-4-yl]ethyl]propanamide
CFAMM00559395 ZINC04043180 Natural Product AC1OEL07
CFAMM00559388 ZINC04073438 Natural Product AC1OF2HB
CFAMM00559401 ZINC04043177 Natural Product N-(2-(2-isopropyl-4-(p-tolyl)tetrahydro-2H-pyran-4-yl)ethyl)-N-(4-methoxybenzyl)propionamide
CFAMM00559394 ZINC04061067 Natural Product N-(4-isopropoxybenzyl)-3-(4-isopropyl-2,2-dimethyltetrahydro-2H-pyran-4-yl)-N-propionylpropanamide
CFAMM00559387 ZINC04073439 Natural Product N-(2-(2-ethyl-4-isopropyl-2-methyltetrahydro-2H-pyran-4-yl)ethyl)-N-(4-methoxybenzyl)propionamide
CFAMM00559400 ZINC04043179 Natural Product AC1OEL04
CFAMM00559393 ZINC04061931 Natural Product AC1OETAC
CFAMM00559386 ZINC12660988 Natural Product N-[(3R)-3-(2-methoxyphenyl)-3-(4-methoxyphenyl)propyl]-N-[(4-propan-2-yloxyphenyl)methyl]propanamide
CFAMM00559399 ZINC12660776 Natural Product N-(3-(4-isopropoxyphenyl)-3-(2-methoxyphenyl)propyl)-N-(4-methoxybenzyl)propionamide
CFAMM00559392 ZINC04061932 Natural Product N-acetyl-N-(4-isopropoxybenzyl)-3-(4-isopropyl-2,2-dimethyltetrahydro-2H-pyran-4-yl)propanamide
CFAMM00559385 ZINC04061066 Natural Product AC1OES05
CFAMM00559398 ZINC04073441 Natural Product N-[2-[(2R,4R)-2-ethyl-2-methyl-4-propan-2-yloxan-4-yl]ethyl]-N-[(4-methoxyphenyl)methyl]propanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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