CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP1386
Family Name NP 3-((1-(3-(2-(pyridin-3-yl)piperidin-1-yl)prop-1-yn-1-yl)cyclohexyl)oxy)propanenitrile Family
No. of Seeds 12 No. of Other Members 0
Family Centroid CFAMM00559761 Functional Category Natural Product
Superfamily NP 3-((1-(3-(2-(pyridin-3-yl)piperidin-1-yl)prop-1-yn-1-yl)cyclohexyl)oxy)propanenitrile and NP 2-methyl-5-(2-(pyridin-3-yl)piperidin-1-yl)pent-3-yn-2-yl Acetate Superfamily
Class Class 484

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 2C ligand Tetracyclic antidepress... 14 498
Nicotinic acetylcholine receptor Ligand Nicotine Family 14 686
Histamine H1 receptor Ligand Pheniramine Family 10 380
Histamine H1 receptor Ligand Triprolidine Family 19 316
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor Ethion... 5 68
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 2 11
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 14 22
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 13 26
Protein kinase C theta type Inhibitor 4-(3h-indol-4-ylamino)-5... 2 2
Acetylcholinesterase and Cholinesterase Inhibitor 1,9-bis(pyri... 8 38
Cytochrome P450 11B1, mitochondrial Inhibitor 2-methyl-1,2-di-... 8 15
Metabotropic glutamate receptor 5 Ligand 3-m-tolyl-1,5-naphthy... 6 10
Metabotropic glutamate receptor 5 Ligand 5-((6-methylpyridin-2... 14 22
Choline kinase alpha Inhibitor Bisquinolinium Derivative Family 10 7
Metabotropic glutamate receptor 5 ligand AGN-PC-075X3R family 1 1
Neuronal acetylcholine receptor subunit alpha-6 ligand AGN-PC-... 2 0
Glucose-dependent insulinotropic receptor ligand tert-butyl 4-... 2 1
Putative NP ZINC38570085 Family 14 0
NP 2-methyl-5-(2-(pyridin-3-yl)piperidin-1-yl)pent-3-yn-2-yl A... 8 1
Putative NP ZINC19701930 Family 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00559769 ZINC58482552 Natural Product AC1LWPCI
CFAMM00559762 ZINC55382701 Natural Product 3-((5-(2-(pyridin-3-yl)piperidin-1-yl)pent-3-yn-1-yl)oxy)propanenitrile
CFAMM00559768 ZINC58482553 Natural Product 3-((4-(2-(pyridin-3-yl)piperidin-1-yl)but-2-yn-1-yl)oxy)propanenitrile
CFAMM00559761 ZINC12342069 Natural Product AC1LWZSZ
CFAMM00559767 ZINC55382697 Natural Product AC1LXU1A
CFAMM00559760 ZINC55214594 Natural Product 3-[(2R)-6-[(2R)-2-pyridin-3-ylpiperidin-1-yl]hex-4-yn-2-yl]oxypropanenitrile
CFAMM00559766 ZINC61997645 Natural Product AC1O46VB
CFAMM00559759 ZINC55236087 Natural Product 3-((2-methyl-5-(2-(pyridin-3-yl)piperidin-1-yl)pent-3-yn-2-yl)oxy)propanenitrile
CFAMM00559765 ZINC61997644 Natural Product 3-((3-methyl-6-((S)-2-(pyridin-3-yl)piperidin-1-yl)hex-4-yn-3-yl)oxy)propanenitrile
CFAMM00559758 ZINC55214591 Natural Product 3-[(2S)-6-[(2R)-2-pyridin-3-ylpiperidin-1-yl]hex-4-yn-2-yl]oxypropanenitrile
CFAMM00559764 ZINC55231603 Natural Product AC1LX2TF
CFAMM00559763 ZINC57547143 Natural Product 3-((1-(3-(2-(pyridin-3-yl)piperidin-1-yl)prop-1-yn-1-yl)cyclohexyl)oxy)propanenitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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