CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP1407
Family Name 6,7-dihydropyrimido[6,1-a]isoquinolin-4-one NP ZINC02112138 Family
No. of Seeds 10 No. of Other Members 0
Family Centroid CFAMM00559906 Functional Category Natural Product
Superfamily 9,10-dimethoxy-6,7-dihydropyrimido[6,1-a]isoquinolin-4-one NP 2-(4-(benzyloxy)phenoxy)-9,10-dimethoxy-6,7-dihydro-4h-pyrimido[6,1-a]isoquinolin-4-one and 6,7-dihydropyrimido[6,1-a]isoquinolin-4-one NP ZINC02112138 Superfamily
Class Class 3647

Cousin Family NamesSeedsMembers
Leukotriene B4 receptor 1 Ligand Ltb 019 Family 3 35
C-C chemokine receptor type 5 Ligand E-913 Family 6 44
Neutrophil elastase Inhibitor N,n-bis(cyanomethyl)-3,4-dimetho... 3 30
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Kappa-type opioid receptor and Delta-type opioid receptor liga... 1 3
2-(2,4-dimethoxyphenyl)-2,3,6,7,11,12-hexahydro-[1,4]dioxepino... 3 0


External ID

Functional Category

Molecule Name

CFAMM00559911 ZINC02130533 Natural Product 9,10-dimethoxy-2-(4-pentanoylphenoxy)-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one
CFAMM00559910 ZINC02112138 Natural Product AC1LX7SA
CFAMM00559909 ZINC02112137 Natural Product N-(9,10-dimethoxy-4-oxo-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-2-yl)-N-(3-(furan-2-yl)-3-(p-tolyl)propyl)acetamide
CFAMM00559915 ZINC02137860 Natural Product 4-((9,10-dimethoxy-4-oxo-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-2-yl)oxy)-3-ethoxybenzaldehyde
CFAMM00559908 ZINC02135095 Natural Product 2-(4-butyrylphenoxy)-9,10-dimethoxy-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one
CFAMM00559914 ZINC02114518 Natural Product AC1LXBDN
CFAMM00559907 ZINC02127380 Natural Product 2-(4-acetylphenoxy)-9,10-dimethoxy-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one
CFAMM00559913 ZINC02131444 Natural Product 4-((9,10-dimethoxy-4-oxo-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-2-yl)oxy)-3-methoxybenzaldehyde
CFAMM00559906 ZINC02129778 Natural Product 3-((9,10-dimethoxy-4-oxo-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-2-yl)oxy)-4-methoxybenzaldehyde
CFAMM00559912 ZINC02114516 Natural Product 2-((3-(furan-2-yl)-3-(2-methoxyphenyl)propyl)amino)-9,10-dimethoxy-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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