CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP1464
Family Name NP Methyl 2-((3s,3a'r,8a's,8b's)-5-ethyl-1',2,3'-trioxo-3',3a',6',7',8',8a'-hexahydro-1'h-spiro[indoline-3,4'-pyrrolo[3,4-a]pyrrolizine]-2'(8b'h)-yl)benzoate Family
No. of Seeds 7 No. of Other Members 0
Family Centroid CFAMM00560373 Functional Category Natural Product
Superfamily NP 4-((3s,3a'r,8a's,8b's)-5-chloro-7-methyl-1',2,3'-trioxo-3',3a',6',7',8',8a'-hexahydro-1'h-spiro[indoline-3,4'-pyrrolo[3,4-a]pyrrolizine]-2'(8b'h)-yl)phenyl Acetate and NP Methyl 2-((3s,3a'r,8a's,8b's)-7-chloro-5-methyl-1',2,3'-trioxo-3',3a',6',7',8',8a'-hexahydro-1'h-spiro[indoline-3,4'-pyrrolo[3,4-a]pyrrolizine]-2'(8b'h)-yl)benzoate Superfamily
Class Class 6782

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Mefenamic Acid Family 7 137
Caspase-9 and Caspase-8 inhibitor 4-fluoro-2-[[2-[[(2S)-3-meth... 1 11
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 2 1
5-hydroxytryptamine receptor 6 ligand AGN-PC-00ADLV family 1 0
Putative NP ZINC04043929 Family 4 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00560368 ZINC15959057 Natural Product methyl 2-((3S,3a'R,8a'S,8b'S)-5-ethyl-1',2,3'-trioxo-3',3a',6',7',8',8a'-hexahydro-1'H-spiro[indoline-3,4'-pyrrolo[3,4-a]pyrrolizine]-2'(8b'H)-yl)benzoate
CFAMM00560374 ZINC16032831 Natural Product methyl 2-((1'R,3'S,3a'S,6a'R)-3'-benzyl-2,4',6'-trioxo-3a',4',6',6a'-tetrahydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrol]-5'(3'H)-yl)benzoate
CFAMM00560373 ZINC35361887 Natural Product methyl 2-((1'S,3'S,3a'S,6a'R)-3'-methyl-2,4',6'-trioxo-3a',4',6',6a'-tetrahydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrol]-5'(3'H)-yl)benzoate
CFAMM00560372 ZINC20411752 Natural Product methyl 2-((1'S,3a'S,6a'R)-2,4',6'-trioxo-3a',4',6',6a'-tetrahydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrol]-5'(3'H)-yl)benzoate
CFAMM00560371 ZINC33905410 Natural Product methyl 2-((3S,3a'R,8a'S,8b'S)-1',2,3'-trioxo-3',3a',6',7',8',8a'-hexahydro-1'H-spiro[indoline-3,4'-pyrrolo[3,4-a]pyrrolizine]-2'(8b'H)-yl)benzoate
CFAMM00560370 ZINC15958154 Natural Product methyl 2-((3S,3a'R,8a'S,8b'S)-7-ethyl-1',2,3'-trioxo-3',3a',6',7',8',8a'-hexahydro-1'H-spiro[indoline-3,4'-pyrrolo[3,4-a]pyrrolizine]-2'(8b'H)-yl)benzoate
CFAMM00560369 ZINC15958365 Natural Product methyl 2-((1'R,3'S,3a'S,6a'R)-3'-(2-(methylthio)ethyl)-2,4',6'-trioxo-3a',4',6',6a'-tetrahydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrol]-5'(3'H)-yl)benzoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27744 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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