CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP1485
Family Name 12b-methyl-2,3,6,7-tetrahydropyrazino[1',2':1,2]pyrido[3,4-b]indole-1,4(12H,12bH)-dione NP (12bs)-7-(4-bromophenyl)-2-(2-methoxyethyl)-12b-methyl-2,3,6,7-tetrahydropyrazino[1',2':1,2]pyrido[3,4-b]indole-1,4(12h,12bh)-dione Family
No. of Seeds 16 No. of Other Members 0
Family Centroid CFAMM00560522 Functional Category Natural Product
Superfamily Prelamin-A/C and Cholinesterase Binder Superfamily 2
Class Class 173

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
D(2) dopamine receptor ligand ergot alkaloid Cabergoline Family 5 74
Cholecystokinin receptor type A Ligand Tarazepide Family 6 323
Growth hormone receptor Ligand EP-51216 Family 34 390
Histone deacetylase 1 Inhibitor Panobinostat Family 5 93
Lethal factor Inhibitor GM6001 Family 50 435
Cyclin-dependent kinase 5 Inhibitor 9-nitropaullone Family 2 13
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 19 108
cGMP-specific 3',5'-cyclic phosphodiesterase and Dual 3',5'-cy... 4 129
12b-methyl-2,3,6,7-tetrahydropyrazino[1',2':1,2]pyrido[3,4-b]i... 11 0
(S)-2-amino-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4... 1 0
2,3,6,7-tetrahydropyrazino[1',2':1,2]pyrido[3,4-b]indole-1,4(1... 3 0
6-(3-nitrophenyl)-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyri... 16 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00560514 ZINC02108333 Natural Product (12aS)-6-(4-bromophenyl)-2-(3-isopropoxypropyl)-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione
CFAMM00560523 ZINC08789761 Natural Product (12bS)-7-(4-bromophenyl)-2-(2-hydroxyethyl)-12b-methyl-2,3,6,7-tetrahydropyrazino[1',2':1,2]pyrido[3,4-b]indole-1,4(12H,12bH)-dione
CFAMM00560513 ZINC02108334 Natural Product AC1LX2P5
CFAMM00560529 ZINC08789759 Natural Product (12bS)-7-(4-bromophenyl)-2-(2-hydroxyethyl)-12b-methyl-2,3,6,7-tetrahydropyrazino[1',2':1,2]pyrido[3,4-b]indole-1,4(12H,12bH)-dione
CFAMM00560522 ZINC12876481 Natural Product (12bS)-7-(4-bromophenyl)-2-(3-methoxypropyl)-12b-methyl-2,3,6,7-tetrahydropyrazino[1',2':1,2]pyrido[3,4-b]indole-1,4(12H,12bH)-dione
CFAMM00560511 ZINC12873984 Natural Product (12bS)-7-(4-bromophenyl)-2-(2-methoxyethyl)-12b-methyl-2,3,6,7-tetrahydropyrazino[1',2':1,2]pyrido[3,4-b]indole-1,4(12H,12bH)-dione
CFAMM00560528 ZINC12876488 Natural Product (12bS)-7-(4-bromophenyl)-2-(3-methoxypropyl)-12b-methyl-2,3,6,7-tetrahydropyrazino[1',2':1,2]pyrido[3,4-b]indole-1,4(12H,12bH)-dione
CFAMM00560521 ZINC02110842 Natural Product (12aS)-6-(4-bromophenyl)-2-(2-methoxyethyl)-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione
CFAMM00560510 ZINC12873979 Natural Product (12bS)-7-(4-bromophenyl)-2-(2-methoxyethyl)-12b-methyl-2,3,6,7-tetrahydropyrazino[1',2':1,2]pyrido[3,4-b]indole-1,4(12H,12bH)-dione
CFAMM00560527 ZINC02111956 Natural Product (12aS)-6-(4-bromophenyl)-2-(3-ethoxypropyl)-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione
CFAMM00560520 ZINC12877849 Natural Product (12bS)-7-(4-bromophenyl)-2-(3-hydroxypropyl)-12b-methyl-2,3,6,7-tetrahydropyrazino[1',2':1,2]pyrido[3,4-b]indole-1,4(12H,12bH)-dione
CFAMM00560526 ZINC02111958 Natural Product AC1LX7IA
CFAMM00560516 ZINC12875124 Natural Product (12bS)-7-(4-bromophenyl)-2-(5-hydroxypentyl)-12b-methyl-2,3,6,7-tetrahydropyrazino[1',2':1,2]pyrido[3,4-b]indole-1,4(12H,12bH)-dione
CFAMM00560525 ZINC02110844 Natural Product AC1LX5SB
CFAMM00560515 ZINC08788989 Natural Product (12bS)-7-(4-bromophenyl)-2-(3-hydroxypropyl)-12b-methyl-2,3,6,7-tetrahydropyrazino[1',2':1,2]pyrido[3,4-b]indole-1,4(12H,12bH)-dione
CFAMM00560524 ZINC12875118 Natural Product (12bS)-7-(4-bromophenyl)-2-(5-hydroxypentyl)-12b-methyl-2,3,6,7-tetrahydropyrazino[1',2':1,2]pyrido[3,4-b]indole-1,4(12H,12bH)-dione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27029 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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