CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP1563
Family Name 8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one NP 6,7-dimethoxy-13-(2-methylallyl)-12-((2-methylallyl)oxy)-8h-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one Family
No. of Seeds 47 No. of Other Members 0
Family Centroid CFAMM00561135 Functional Category Natural Product
Superfamily Cyclin-dependent kinase 4 and Cyclin-dependent kinase 2 inhibitor SureCN3569311 Superfamily
Class Class 3477

Cousin Family NamesSeedsMembers
DNA Binder Primaquine Family 3 245
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Platelet-derived growth factor receptor alpha and Platelet-der... 2 17
Vascular endothelial growth factor receptor 2 and Aurora kinas... 3 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00561142 ZINC08792514 Natural Product 6,7-dimethoxy-13-(2-methylallyl)-12-((2-methylallyl)oxy)-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561155 ZINC08792276 Natural Product 12-(benzyloxy)-6,7-dimethoxy-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561122 ZINC08792398 Natural Product 12-((2-chloro-6-fluorobenzyl)oxy)-6,7-dimethoxy-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561135 ZINC06624282 Natural Product 12-ethoxy-6,7-dimethoxy-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561148 ZINC06623672 Natural Product 6,7-dimethoxy-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561161 ZINC06624356 Natural Product 6,7-dimethoxy-8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl acetate
CFAMM00561141 ZINC08792516 Natural Product methyl 2-((6,7-dimethoxy-13-(2-methylallyl)-8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)acetate
CFAMM00561115 ZINC06624314 Natural Product 6,7,11-trimethoxy-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561128 ZINC08792489 Natural Product methyl 2-((6,7-dimethoxy-13-(2-methylallyl)-8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)propanoate
CFAMM00561154 ZINC08792277 Natural Product 12-((2,6-dichlorobenzyl)oxy)-6,7-dimethoxy-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561121 ZINC08792397 Natural Product 12-(cinnamyloxy)-6,7-dimethoxy-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561134 ZINC08792439 Natural Product 12-((2,4-dichlorobenzyl)oxy)-6,7-dimethoxy-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561147 ZINC08764730 Natural Product isopropyl 2-((6,7-dimethoxy-13-(2-methylallyl)-8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)acetate
CFAMM00561160 ZINC06624535 Natural Product 12-butoxy-6,7-dimethoxy-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561127 ZINC08792488 Natural Product methyl 2-((6,7-dimethoxy-13-(2-methylallyl)-8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)propanoate
CFAMM00561140 ZINC08792147 Natural Product 1-(4-ethoxy-3-methoxyphenyl)-6,7-dimethoxy-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561153 ZINC08792270 Natural Product methyl 2-((6,7-dimethoxy-8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)propanoate
CFAMM00561120 ZINC08792402 Natural Product 12-((2-chloroallyl)oxy)-6,7-dimethoxy-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561133 ZINC08765514 Natural Product 12-(cinnamyloxy)-6,7-dimethoxy-13-(2-methylallyl)-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561146 ZINC08792148 Natural Product 1-(2-chlorophenyl)-6,7-dimethoxy-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561159 ZINC08792115 Natural Product ethyl 2-((6,7-dimethoxy-8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)acetate
CFAMM00561126 ZINC08792415 Natural Product methyl 4-(((6,7-dimethoxy-8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)methyl)benzoate
CFAMM00561139 ZINC08792144 Natural Product 6,7-dimethoxy-12-((4-vinylbenzyl)oxy)-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561152 ZINC08792312 Natural Product ethyl 2-((6,7-dimethoxy-8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)propanoate
CFAMM00561119 ZINC08792395 Natural Product 12-((3-chlorobenzyl)oxy)-6,7-dimethoxy-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561132 ZINC08792325 Natural Product methyl 2-((6,7-dimethoxy-8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)acetate
CFAMM00561158 ZINC08792118 Natural Product 6,7-dimethoxy-1-(4-methoxyphenyl)-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561145 ZINC08792519 Natural Product 6,7,12-trimethoxy-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561125 ZINC06624595 Natural Product 6,7-dimethoxy-12-((2-methylallyl)oxy)-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561138 ZINC06624541 Natural Product 12-fluoro-6,7-dimethoxy-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561151 ZINC08792272 Natural Product isopropyl 2-((6,7-dimethoxy-8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)acetate
CFAMM00561118 ZINC08792313 Natural Product ethyl 2-((6,7-dimethoxy-8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)propanoate
CFAMM00561131 ZINC08792322 Natural Product allyl 2-((6,7-dimethoxy-8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)acetate
CFAMM00561144 ZINC08792166 Natural Product 1-(4-ethylphenyl)-6,7-dimethoxy-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561157 ZINC08792235 Natural Product 1-(2-ethoxy-3-methoxyphenyl)-6,7-dimethoxy-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561137 ZINC06624326 Natural Product 6,7-dimethoxy-12-((3-oxobutan-2-yl)oxy)-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561150 ZINC08792492 Natural Product 6,7-dimethoxy-13-(2-methylallyl)-12-((3-oxobutan-2-yl)oxy)-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561124 ZINC06624626 Natural Product 6,7-dimethoxy-12-propoxy-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561117 ZINC06624316 Natural Product 12-hydroxy-6,7-dimethoxy-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561130 ZINC08792269 Natural Product methyl 2-((6,7-dimethoxy-8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)propanoate
CFAMM00561143 ZINC06624327 Natural Product 6,7-dimethoxy-12-((3-oxobutan-2-yl)oxy)-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561156 ZINC08792372 Natural Product 6,7-dimethoxy-1-(3-methoxy-4-propoxyphenyl)-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561123 ZINC08792399 Natural Product 12-((4-chlorobenzyl)oxy)-6,7-dimethoxy-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561136 ZINC08792451 Natural Product 6,7,12-trimethoxy-13-(2-methylallyl)-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561149 ZINC08792494 Natural Product 6,7-dimethoxy-13-(2-methylallyl)-12-((3-oxobutan-2-yl)oxy)-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561116 ZINC06624315 Natural Product 6,7-dimethoxy-1-phenyl-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one
CFAMM00561129 ZINC08764524 Natural Product 6,7-dimethoxy-13-(2-methylallyl)-12-(2-oxopropoxy)-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-8-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

42686 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543