CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP1650
Family Name NP 3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-6-ethyl-4-oxo-4h-chromen-7-yl 4-chlorobenzoate Family
No. of Seeds 33 No. of Other Members 4
Family Centroid CFAMM00561725 Functional Category Natural Product
Superfamily 1-benzofuran-3-one NP (z)-2-(4-chlorobenzylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl Furan-2-carboxylate and orobenzoate NP 3-(2-methoxyphenyl)-2-methyl-4-oxo-4h-chromen-7-yl 2-chlorobenzoate Superfamily
Class Class 2438

Cousin Family NamesSeedsMembers
Heat shock protein 90, putative Inhibitor Cromoglicate Family 14 2827
DNA Binder Methoxsalen Family 10 1638
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Hidrosmin family 14 61
Ipriflavone family 62 2480
Rotenone family 16 107
Agrimophol family 10 22
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Arachidonate 5-lipoxygenase Inhibitor Lonapalene Family 1 31
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Interleukin-1 beta Inhibitor Diacerein Family 3 77
Endothelin-1 receptor Ligand PD156707 Family 41 211
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 2,5-... 2 96
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Ellagi... 1 11
Fatty acid-binding protein, adipocyte and Fatty acid-binding p... 4 102
MO15-related protein kinase Pfmrk Inhibitor WR-289012 Family 2 17
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Protein farnesyltransferase subunit beta Inhibitor Cylindrol A... 3 43
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
CGMP-dependent protein kinase Inhibitor Tenellone A Family 1 7
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
Cholesteryl ester transfer protein inhibitor [8-[(1S)-1-hydrox... 1 0
NP 7'-((2,6-dichlorobenzyl)oxy)-8-methoxy-2h,2'h-[3,4'-bichrom... 3 1
NP (z)-2-(2,3-dimethoxybenzylidene)-3-oxo-2,3-dihydrobenzofura... 9 0
1,3-dimethylcyclohepta[c]furan-8-one NP 6-(4-hydroxy-3-iodo-5-... 13 1
NP 2-((3-(3,4-dihydro-2h-benzo[b][1,4]dioxepin-7-yl)-6-ethyl-4... 10 0
NP 4-(((3-(4-chlorophenyl)-2-methyl-4-oxo-4h-chromen-7-yl)oxy)... 14 0
NP (z)-6-((4-bromobenzyl)oxy)-2-(3,4-dimethoxybenzylidene)benz... 13 2
NP (z)-2-((2-methyl-2h-chromen-3-yl)methylene)-3-oxo-2,3-dihyd... 74 1
1-benzofuran-3-one NP (z)-2-(4-chlorobenzylidene)-3-oxo-2,3-di... 27 0
NP 2-((3-(3,4-dihydro-2h-benzo[b][1,4]dioxepin-7-yl)-2-methyl-... 2 0
benzenesulfonate NP (z)-3-oxo-2-(3,4,5-trimethoxybenzylidene)-... 26 0
NP Ethyl 7-((2-chlorobenzoyl)oxy)-3-(2-methoxyphenyl)-4-oxo-4h... 37 1
orobenzoate NP 3-(2-methoxyphenyl)-2-methyl-4-oxo-4h-chromen-7... 22 0
NP 4-(3,4-dimethoxyphenyl)-4-oxo-2-(3,4,5-trimethoxyphenyl)but... 2 3
3-[2-(5-chloro-2-hydroxyphenyl)-2-oxoethyl]-6,7-dimethoxy-3H-2... 2 0
Putative NP ZINC05155929 Family 6 0
bromobenzoate NP ZINC09346025 Family 20 0
Putative NP ZINC13787156 Family 4 0
1-benzofuran-3-one NP ZINC02423517 Family 24 0
NP Af-399/42316321 Family 7 0
2-(trifluoromethyl)chromen-4-one NP ZINC01929476 Family 25 0
1-benzofuran-3-one NP ZINC02424004 Family 22 0
Putative NP ZINC02424496 Family 5 0
Putative NP ZINC09051797 Family 10 0
NP 2-amino-7-[(2,6-dichlorophenyl)methoxy]-3-(4-methoxyphenyl)... 4 0
NP 3-(4-bromophenyl)-4-oxo-4h-chromen-7-yl 4-chlorobenzoate Fa... 17 0
Putative NP ZINC02417403 Family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00561705 ZINC11866299 Natural Product STOCK6S-00070
CFAMM00561696 ZINC02201103 Natural Product 7-[(2-chlorobenzyl)oxy]-3-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-6-ethyl-4H-chromen-4-one
CFAMM00561719 ZINC01940888 Natural Product ST50472151
CFAMM00561712 ZINC02667591 Natural Product AC1MSXUY
CFAMM00561725 ZINC01463870 Natural Product AC1LTM4U
CFAMM00561695 ZINC01800997 Natural Product AC1LUOIR
CFAMM00561704 ZINC01463828 Natural Product ST50039620
CFAMM00561718 ZINC01463883 Natural Product 7-[(2-chloro-4-fluorobenzyl)oxy]-3-(3,4-dimethoxyphenyl)-2-methyl-4H-chromen-4-one
CFAMM00561710 ZINC02107480 Natural Product 7-(2-(4-chlorophenyl)-2-oxoethoxy)-3-(3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-yl)-6-ethyl-4H-chromen-4-one
CFAMM00561694 ZINC02387237 Natural Product AC1M04OB
CFAMM00561703 ZINC02199174 Natural Product 7-[2-(4-chlorophenyl)-2-oxoethoxy]-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-4H-chromen-4-one
CFAMM00561717 ZINC02375544 Natural Product AC1LZWV0
CFAMM00561723 ZINC02200753 Natural Product 7-[(2-chloro-4-fluorobenzyl)oxy]-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-6-ethyl-2-methyl-4H-chromen-4-one
CFAMM00561709 ZINC02667497 Natural Product AC1MXK39
CFAMM00561693 ZINC01924867 Natural Product ST50472150
CFAMM00561716 ZINC02667598 Natural Product ST50472133
CFAMM00561699 ZINC02200996 Natural Product 7-[(2-chloro-6-fluorobenzyl)oxy]-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-6-ethyl-4H-chromen-4-one
CFAMM00561708 ZINC01463825 Natural Product 3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-6-ethyl-4-oxo-4H-chromen-7-yl 4-chlorobenzoate
CFAMM00561722 ZINC02397319 Natural Product 7-[(2-chloro-6-fluorobenzyl)oxy]-3-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-6-ethyl-4H-chromen-4-one
CFAMM00561701 ZINC02203526 Natural Product AC1LXU0U
CFAMM00561715 ZINC02157459 Natural Product AC1LXR9G
CFAMM00561692 ZINC02204112 Natural Product AC1LXUSC
CFAMM00561698 ZINC02264037 Natural Product AC1LZ2S4
CFAMM00561707 ZINC11865193 Natural Product ST50472062
CFAMM00561721 ZINC02107526 Natural Product 7-[(3-chlorobenzyl)oxy]-3-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-6-ethyl-4H-chromen-4-one
CFAMM00561727 ZINC02107241 Natural Product 7-[(2-chloro-6-fluorobenzyl)oxy]-3-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-6-propyl-4H-chromen-4-one
CFAMM00561691 ZINC01924869 Natural Product ST50472148
CFAMM00561700 ZINC02394044 Natural Product 7-[(2-chloro-6-fluorobenzyl)oxy]-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-6-propyl-4H-chromen-4-one
CFAMM00561706 ZINC11866298 Natural Product STOCK5S-99694
CFAMM00561697 ZINC02200950 Natural Product 7-[(4-chlorobenzyl)oxy]-3-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-6-ethyl-4H-chromen-4-one
CFAMM00561720 ZINC01792428 Natural Product 7-[(2,4-dichlorobenzyl)oxy]-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-6-ethyl-2-methyl-4H-chromen-4-one
CFAMM00561713 ZINC09266649 Natural Product AC1NKGA9
CFAMM00561726 ZINC11865225 Natural Product ST50472100

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27076 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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